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Table 1 Baseline characteristics of the included study population

From: Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study

Patient characteristics

Total

157

 Age, median (IQR)

75.3 (70.8–80.8)

 Male gender, n (%)

103 (65.6)

 Caucasian origin, n (%)

138 (89.0)

 Married/living together, n (%)

94 (61.4)

 Higher Educational level, n (%)

48 (30.6)

 Current smoking

23 (15.0)

 Alcohol consumption

77 (50.3)

Disease specific

 eGFR at study enrolment, mean (SD)

16.2 (4.4)

 Δ eGFR (ml/min), mean (SD)a

9.1 (8.0)

Primairy kidney disease

  Non-vascular cause, n (%)

56 (35.7)

  Vascular cause, n (%)

99 (63.1)

 Diabetes mellitus, n (%)

63 (40.1)

 (history of) malignancy, n (%)

47 (29.9)

 History of vascular disease, (n%)

74 (47.4)

 Ankle-brachial index (right), mean (SD)

0.96 (0.23)

Medication use

 Polypharmacy (the use of ≥5 medications), n (%)

139 (89.7)

 Glucose lowering medication, n (%)

54 (34.4)

 Antihypertensive medication, n (%)

145 (92.4)

 Diuretics, n (%)

94 (60.3)

 Cholesterol lowering drugs, n (%)

112 (71.3)

 Vitamin D supplement, n (%)

131 (83.4)

Nutrition status

 Normal Subjective Global Assessment (SGA) score

42 (49.4)

SNAQ score

  Malnourished

8 (10.7)

  Risk for malnutrition

9 (12.0)

 BMI, median (IQR)

27.4 (24.6–30.9)

 Special diet, n (%)

127 (83.0)

Geriatric assessment

 Frail according to FFI, n (%)

37 (24.5)

 Functional dependence by GARS-score, mean (IQR)

26 (20.0–35.0)

 Dependent in IADL function, n (%)

8 (5.0)

Handgrip strength (kg), mean (SD)

  Females

17.2 (6.3)

  Males

29.4 (8.1)

 Walking speed, mean (SD) (m/s)

1.13 (0.98)

  1. aΔ eGFR = difference between eGFR 3 years before and at study enrolment. Abbreviations: IQR Interquartile range, eGFR Estimated glomerular filtration rate, SNAQ Short Nutritional Assessment Questionnaire, BMI Body mass index, FFI Fried Frailty Index, GARS-score Groningen Activity Restriction Score, IADL Instrumental Activities of Daily Living. Data complete for; race (n = 155), level of education (n = 153), marital status (n = 153), smoking and alcohol consumption (n = 153), eGFR (n = 151), primary kidney disease unknow n = 2, polypharmacy (n = 155), diet (n = 153), SGA-score (n = 85), SNAQ = score (n = 75), Fried Frailty Index (n = 141), Handgrip strength (n = 152), walking speed (n = 145)