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Table 2 Associated characteristics of memory function

From: Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study

 

Memory function

P-value

Best tertile

N = 51

Middle tertile

N = 54

Worst tertile

N = 50

crude

adjusted

Age, mean (SE)

73.8 (0.9)

75.8 (0.9)

78.7 (0.9)

< 0.001

< 0.001*

Gender, n (%)

   

0.032

0.003*

 Female

19 (37.3%)

21 (38.9%)

13 (26%)

  

 Male

32 (63.7%)

33 (61.1%)

37 (74%)

  

Higher educational level, n (%)

17 (33.3%)

20 (37.0%)

10 (20.0%)

0.003

0.001*

eGFR, mean (SE)

16.4 (0.7)

16.1 (0.6)

16.2 (0.6)

0.922

0.664

ΔeGFR, mean (SE)

10.1 (1.7)

8.3 (1.0)

9.1 (1.0)

0.598

0.779

Urea, mean (SE)

20.4 (0.8)

20.9 (0.9)

21.7 (0.8)

0.904

0.582

Phosphate, mean (SE)

1.3 (0.04)

1.3 (0.03)

1.3 (0.04)

0.258

0.527

Calcium, mean (SE)

2.3 (0.02)

2.4 (0.02)

2.3 (0.02)

0.401

0.547

Vascular vs non-vascular cause, n (%)

   

0.946

0.884

 Vascular

28 (56.0%)

39 (72.2%)

31 (63.2%)

  

 Non-vascular

22 (44.0%)

15 (27.7%)

18 (36.7%)

  

Ankle-Brachial index (right), mean (SE)

0.98 (0.03)

0.90 (0.04)

0.99 (0.04)

0.526

0.572

Presence of diabetes, n (%)

18 (35.3%)

24 (44.4%)

21 (42.0%)

0.195

0.286

History of vascular disease, n (%)

19 (37.3%)

26 (48.1%)

28 (56%)

0.004

0.163

Polypharmacy (≥5), n (%)

43 (84.2%)

51 (94.4)

44 (88%)

0.622

0.512

Fried Frailty Index, mean (SE)

1.3 (0.2)

1.6 (0.2)

1.9 (0.2)

0.055

0.082

IADL, mean (SE)

2.0 (0.4)

3.2 (0.5)

4.6 (0.6)

< 0.001

0.003

Walking speed, mean (SE)

1.2 (0.05)

1.0 (0.04)

1.2 (0.25)

0.795

0.545

Handgrip strength, mean (SE)

25.5 (1.4)

24.4 (1.3)

26.1 (1.4)

0.527

0.529

  1. Memory tested by the 15-WVLT. Tertiles of the 15-WVLT: best tertile mean 42.6 (SD 6.3) n = 51; middle tertile mean 29.7 (SD 2.8) n = 54; worst tertile mean 21 (SD 3.9) n = 50 Δ EGFR available for n = 41, n = 48, n = 39. Ankle-Brachial index available for n = 35, n = 37, n = 39. Walking speed available for n = 46, n = 50, n = 47. Model I: linear regression including correction for age, gender and educational level. *In model I age is only adjusted for gender and educational level; gender is only adjusted for age and educational level; educational level is only adjusted for age and gender