From: The impact of hyperglycemia on urinary albumin excretion in recent onset diabetes mellitus type II
Variable | All patients (n = 71) | Hypertensive patients with diabetes (n = 44) | Normotensive patients with diabetes (n = 27) | P value |
---|---|---|---|---|
Age (years) | 56.6 ± 10.4 | 57.1 ± 11.3 | 55.7 ± 8.9 | 0.584 |
Male sex (%) | 57.7 | 59.8 | 59.3 | 0.840 |
Duration of diabetes (months) | 1 (0–5) | 0 (0–3.5) | 1 (0–6) | 0.199 |
Fasting glucose (mg/dl) | 120 (104–137) | 121 (100.5–133.5) | 112 (105.5–155) | 0.691 |
HbA1c (%) | 6.7 (6.3–7.5) | 6.7 (6.3–7.4) | 6.7 (6.3–7.7) | 0.803 |
Metformin (%) | 47.9 | 45.5 | 51.9 | 0.600 |
BMI (kg/m2) | 30.3 ± 4.2 | 31.1 (28.5–33.8) | 29.5 ± 3.9 | 0.049 |
Duration of hypertension (years) | 8 (4–12) | 8 (4–12) | ΝΑ | ΝΑ |
Office SBP (mmHg) | 137.6 ± 20.5 | 142.5 ± 21.1 | 129.0 ± 16.2 | 0.008 |
Office DBP (mmHg) | 84.0 ± 11.9 | 87.0 ± 12.7 | 78.8 ± 8.1 | 0.002 |
Daytime SBP (mmHg) | 129.2 ± 16.1 | 134.5 ± 16.7 | 120.0 ± 9.8 | < 0.001 |
Daytime DBP (mmHg) | 79.1 ± 11.5 | 82.0 ± 12.8 | 74.1 ± 6.3 | 0.001 |
Nighttime SBP (mmHg) | 120.2 ± 16.7 | 125.3 ± 16.9 | 110.2 ± 11.1 | < 0.001 |
Nighttime DBP (mmHg) | 71.3 ± 10.8 | 73.9 ± 11.3 | 66.3 ± 8.1 | 0.007 |
UAE (mg/24 h) | 7.5 (2.9–17.3) | 9.1 (3.7–17.8) | 5.1 (2.5–8.7) | 0.147 |
PWV (m/s) | 8.9 ± 1.8 | 8.8 (7.3–10.2) | 8.5 ± 1.3 | 0.087 |
Total cholesterol (mg/dl) | 190.9 ± 38.4 | 191.4 ± 36.3 | 190.0 ± 42.5 | 0.880 |
LDL cholesterol (mg/dl) | 121.2 ± 33.8 | 121.9 ± 29.0 | 120.0 ± 41.2 | 0.826 |
HDL cholesterol (mg/dl) | 41.3 ± 11.1 | 41.0 ± 10.9 | 41.8 ± 11.8 | 0.749 |
Triglycerides (mg/dl) | 122 (102–174) | 134.5 (103.5–187) | 113.0 (102–161) | 0.208 |
Urea (mg/dl) | 31.2 ± 6.9 | 31.2 ± 7.1 | 31.1 ± 6.8 | 0.927 |
Creatinine (mg/dl) | 0.88 ± 0.16 | 0.86 ± 0.15 | 0.92 ± 0.18 | 0.114 |
GFR (mL/min/1.73 m2) | 111.6 ± 34.8 | 116.7 ± 38.0 | 103.4 ± 27.5 | 0.126 |
Uric acid (mg/dl) | 5.4 ± 1.7 | 5.5 ± 1.5 | 5.2 ± 1.99 | 0.458 |
Antihypertensive medication (%) | NA | NA | ||
RAAS inhibitors (%) | 22.5 | 36.4 | NA | NA |
b-blockers (%) | 2.8 | 4.5 | NA | NA |
Calcium channel blockers (%) | 8.5 | 13.6 | NA | NA |