Table 4 Patient characteristics with endotoxin, (1–3)-β-D glucan, inflammatory cytokines, and symptoms pre- and post- initiation of haemodialysis
From: Beta-glucans in advanced CKD: role in endotoxaemia and inflammation
Parameter (n = 29) | Value | ||
|---|---|---|---|
Age (year) | 56 ± 16 | ||
Male gender (%) | 69 | ||
Charlson Comorbidity Index | 5 [3–5] | ||
Weight (kg) | 87 ± 17 | ||
Before HD | Post HD initiation | p-value | |
Sample time (months) | 0 [0.28] | 2.8 [2.3] | – |
BG (pg/mL) | 26 [17] | 41 [22.5] | 0.002 |
IL-6 (pg/mL) | 5.9 [9.7] | 7.3 [7.8] | NS |
TNF-α (pg/mL) | 19.4 [7.5] | 21.9 [7.1] | 0.008 |
CRP (mg/L) | 5 [10.7] | 5.6 [9.8] | NS |
Endotoxin (EU/mL) (without BG blockade) | 0 [0.032] | 0 [0.026] | NS |
Detectable endotoxemia (without BG blockade) [%] | 31 (9/29) | 28 (8/29) | NS |
Detectable endotoxemia (with BG blockade) [%] | 0 (0/29) | 3.4 (1/29) | NS |