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Table 4 Association of urine markers with eGFR among n = 30 PH patients

From: Urinary monocyte chemoattractant protein 1 associated with calcium oxalate crystallization in patients with primary hyperoxaluria

BiomarkeraeGFR
Estimate (95% CI)P
Clusterin1.186 (− 0.42, 2.793)0.15
Clusterin/Cr1.377 (−0.347, 3.102)0.12
NGAL2.598 (1.118, 4.077)< 0.001
NGAL/Cr2.207 (0.56, 3.855)0.009
8 IP4.586 (0.05, 9.121)0.054
8 IP/Cr2.509 (−2.34, 7.358)0.31
MCP-11.698 (−0.569, 3.966)0.14
MCP-1/Cr1.507 (−0.523, 3.536)0.15
L-FABP−3.542 (−10.156, 3.072)0.29
L-FABP/Cr−4.23 (−8.317, −0.143)0.043
OPN2.543 (0.751, 4.334)0.005
OPN/Cr2.223 (0.77, 3.676)0.003
H-FABP1.799 (−3.621, 7.218)0.52
H-FABP/Cr0.52 (−3.706, 4.746)0.81
  1. P-values in bold denote significance at the 0.05 level
  2. Models were fit using the GEE procedure with the normal distribution, identity link and exchangeable correlation specifications, unless noted otherwise
  3. Models were adjusted for age and sex
  4. aLog transformations were taken for all urine biomarkers as well as Uox, PTOx, Calcium/Cr and Citrate/Cr
  5. Units of measure are Clusterin: ng/ml and μg/g Cr; NGAL ng/ml and ng/g Cr, 8 IP pg/ml and ng/g Cr, MCP1 pg/ml and pg/g Cr, L-FABP ng/ml and μg/g Cr, OPN ng/ml and μg/g Cr, H-FABP pg/ml and ng/g Cr