Roles of peritoneal clearance and residual kidney removal in control of uric acid in patients on peritoneal dialysis

Table 4 Associated factors of peritoneal UA clearance in multiple linear regression in total, lower and higher mGFR patients, respectively

Variables	Total		Lower mGFR group^a		Higher mGFR group
Variables	β (95%CI)	P value	β (95%CI)	P value	β (95%CI)	P value
mGFR (mL/min/1.73m²)	− 0.08 (− 0.67, 0.18)	0.26	–	–	–	–
Age (y)	0.16 (0.02, 0.15)	0.01	0.10(− 0.03, 0.13)	0.23	0.24 (0.02, 0.26)	0.02
Sex (M/F)	−0.12 (− 3.35, 0.02)	0.053	− 0.14(− 3.97, 0.44)	0.12	−0.11(− 4.22,1.14)	0.26
Using diuretics	− 0.04 (− 3.04, 1.64)	0.56	− 0.007(− 3.04, 2.82)	0.94	−0.06(− 5.20,2.64)	0.52
Albumin (g/dL)	−0.15 (− 4.99, − 0.31)	0.03	−0.24(− 7.26, − 0.99)	0.01	−0.05(− 4.57,2.85)	0.64
PD vintage (month)	0.07 (−0.02, 0.05)	0.36	0.17(−0.006, 0.06)	0.10	−0.13(− 0.31,0.09)	0.28
BMI (kg/m²)	−0.27 (− 0.87, − 0.33)	<0.001	−0.29(− 0.98, − 0.24)	0.001	−0.32(− 1.10,-0.22)	0.004
Average glucose concentration of dialysate (0.1%)	0.14 (−0.005, 0.87)	0.05	0.19(−0.004, 0.88)	0.052	0.08(−0.70, 1.81)	0.38
Higher peritoneal transport status^b	0.29 (2.40, 6.18)	<0.001	0.24 (0.72, 5.88)	0.01	0.32 (1.77,7.74)	0.002
Dialysis dose (L/d)	0.27 (1.10, 3.36)	<0.001	0.24 (0.26, 3.12)	0.02	0.20(−0.34,4.51)	0.09

Abbreviations: BMI body mass index, CI confidence interval, mGFR measured glomerular filtration rate, PD peritoneal dialysis, UA uric acid
^aDid not adjust mGFR when analyzing in the higher(> 2.74 mL/min/1.73m²) or lower (≤ 2.74 mL/min/1.73m²) mGFR group, respectively
^bThe reference group was the lower (low average or low) peritoneal transporters

ISSN: 1471-2369