Fig. 2From: Clinicopathological characteristics of light chain proximal tubulopathy in Korean patients and the diagnostic usefulness of immunohistochemical staining for immunoglobulin light chainMicroscopic findings of LCPT without crystal. LCPT without crystal shows (a) vacuolization (#3, HE) and (b) diffuse damage (#4; PAS) of the tubule. Diffuse accumulation of λ-LC is observed both in (c) IF and (d) IHC (κ-LC in an inlet) staining in patient #5. e The lysosome in the tubular cytoplasm is increased in number and contains numerous electron-dense deposits, which leads to mottled appearance in patient #4. f Large dysmorphic lysosomes with electron-dense particles are seen in patient #5. Scale bars indicate 10 μm in LM and 1 μm in EM figuresBack to article page