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Fig. 2 | BMC Nephrology

Fig. 2

From: Clinicopathological characteristics of light chain proximal tubulopathy in Korean patients and the diagnostic usefulness of immunohistochemical staining for immunoglobulin light chain

Fig. 2

Microscopic findings of LCPT without crystal. LCPT without crystal shows (a) vacuolization (#3, HE) and (b) diffuse damage (#4; PAS) of the tubule. Diffuse accumulation of λ-LC is observed both in (c) IF and (d) IHC (κ-LC in an inlet) staining in patient #5. e The lysosome in the tubular cytoplasm is increased in number and contains numerous electron-dense deposits, which leads to mottled appearance in patient #4. f Large dysmorphic lysosomes with electron-dense particles are seen in patient #5. Scale bars indicate 10 μm in LM and 1 μm in EM figures

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