Fig. 2From: Secondary oxalosis induced by xylitol concurrent with lithium-induced nephrogenic diabetes insipidus: a case reportPolarized light microscopy showing double-refractive crystals deposited in cortical renal tubules. The crystals have a rosette-like structure (upper panel, arrows). Decreased levels of aquaporin-2 expression are observed in cortical (middle-left panel) and medullary (lower-left panel) renal tubules compared with control (middle and lower-right panel)Back to article page