Table 1 Clinical characteristics of patients across tertiles of AACS
|  | Total (n = 292) | Low AACS group (n = 125) | Medium AACS group (n = 72) | High AACS group (n = 95) | P Value |
|---|---|---|---|---|---|
Age (year) | 57.1 ± 15.2 | 48.5 ± 14.9 | 59.8 ± 12.1 | 66.4 ± 10.8 | < 0.001 |
Male gender, n (%) | 160 (54.8) | 67 (46.4) | 37 (51.4) | 56 (58.9) | 0.586 |
BMI (kg/m2) | 22.4 (20.3, 25.0) | 21.6 (19.7, 24.5) | 22.5 (21.0, 25.5) | 23.1 (21.4, 25.5) | 0.013 |
Dialysis Duration (month) | 28.4 (12.0, 57.8) | 21.7 (7.6, 52.7) | 29.2 (13.6, 56.9) | 41.7 (19.0, 71.0) | 0.004 |
CKD etiology, n (%) | Â | Â | Â | Â | 0.105 |
 Glomerulonephritis | 103(35.3%) | 51(40.8%) | 24(33.3%) | 28(29.5%) |  |
 Polycystic kidney | 9(3.1%) | 5(4.0%) | 3(4.2%) | 1(1.1%) |  |
 Diabetic nephropathy | 43 (14.7%) | 7 (5.6) | 15 (20.8) | 21 (22.1) |  |
 Hypertension | 12(4.1%) | 5(4.0%) | 3(4.2%) | 4(4.2%) |  |
 Others | 10(3.4%) | 5(4.0%) | 1(1.4%) | 4(4.2%) |  |
 Unknown | 115(39.4%) | 52(41.6%) | 26(36.1%) | 37(38.9%) |  |
Hypertension, n (%) | 270 (92.5%) | 110 (88.0%) | 69 (95.8%) | 91 (95.8%) | 0.044 |
Diabetes, n (%) | 75 (25.7%) | 13 (10.4%) | 24 (33.3%) | 38 (50.7%) | < 0.001 |
CVD history, n (%) | 94 (32.2%) | 20 (16.0%) | 28 (38.9%) | 46 (48.9%) | < 0.001 |
Total Kt/V | 1.82 (1.61, 2.11) | 1.84 (1.63, 2.18) | 1.82 (1.65, 2.05) | 1.81 (1.58, 2.07) | 0.292 |
RRF (ml/min) | 0.9 (0.0, 2.9) | 1.0 (0.0, 3.7) | 0.7 (0.0, 2.7) | 0.8 (0.0, 2.0) | 0.204 |
Urine volume (ml/d) | 300 (0, 800) | 375 (0, 988) | 300 (0, 725) | 280 (0, 600) | 0.167 |
Albumin (g/L) | 37.4 (34.6, 40.5) | 38.6 (35.4, 41.5) | 37.8 (34.3, 40.4) | 37.2 (33.2, 39.7) | 0.031 |
hs-CRP (mg/L) | 2.3 (0.7, 5.8) | 1.4 (0.6, 4.5) | 2.9 (1.0, 6.5) | 3.4 (1.2, 7.6) | 0.002 |
Corrected calcium (mmol/L) | 2.35 ± 0.20 | 2.32 ± 0.18 | 2.37 ± 0.21 | 2.37 ± 0.21 | 0.137 |
Phosphorus (mmol/L) | 1.54 (1.26, 1.84) | 1.52 (1.28, 1.87) | 1.47 (1.21, 1.77) | 1.60 (1.25, 1.85) | 0.789 |
iPTH (pg/ml) | 274 (126, 568) | 323 (131, 595) | 300 (99, 527) | 242 (130, 531) | 0.659 |
AKP (U/L) | 85.0 (65.0, 113.0) | 86.5 (65.0, 109.8) | 80.0 (64.0, 104.8) | 89.0 (66.0, 126.0) | 0.221 |
TG (mmol/L) | 1.82 (1.23, 2.79) | 1.65 (1.14, 2.30) | 1.93 (1.24, 2.41) | 2.21 (1.36, 3.26) | 0.007 |
TC (mmol/L) | 5.08 ± 1.19 | 4.99 ± 1.11 | 5.02 ± 1.09 | 5.22 ± 1.35 | 0.346 |
LDL (mmol/L) | 2.86 (2.18, 3.51) | 2.68 (2.18, 3.62) | 2.98 (2.06, 3.58) | 2.96 (2.21,3.38) | 0.963 |
HDL (mmol/L) | 1.11 (0.90, 1.46) | 1.21 (0.95, 1.51) | 1.11 (0.90, 1.40) | 1.00 (0.86, 1.39) | 0.002 |
Use of calcium-based phosphate binder, n (%) | 210 (72.2%) | 94 (75.2%) | 46 (64.8%) | 70 (73.7%) | 0.272 |
Use of Low-calcium dialysate, n (%) | 114 (39.2%) | 48(38.4%) | 24(33.8%) | 42(44.2%) | 0.386 |