Table 3 Association Between Baseline Serum Chloride and Change in eGFR
From: The association between serum chloride levels and chronic kidney disease progression: a cohort study
Linear Regression Model | Parameter Estimate (in mL/min/1.73 m2) | 95% C.I. | P-value |
|---|---|---|---|
Continuous serum chloride (per 1 mEq/L increase) | |||
Unadjusted | −0.315 | (− 0.507, − 0.124) | < 0.001 |
Demographic adjusted | − 0.286 | (− 0.479, − 0.093) | 0.002 |
Fully adjusted | − 0.323 | (− 0.538, − 0.109) | 0.003 |
Chloride quartiles (unadjusted) | |||
1 | Ref | Ref | |
2 | −0.401 | (−2.57, 1.767) | 0.72 |
3 | −1.384 | (−3.657, 0.889) | 0.23 |
4 | −3.215 | (−5.366, −1.064) | 0.004 |
Measured ordinally | −1.115 | (− 1.783, −0.447) | 0.001 |
Chloride quartiles (demographic adjusted) | |||
1 | Ref | Ref | |
2 | −0.118 | (−2.288, 2.051) | 0.91 |
3 | −1.101 | (−3.371, 1.169) | 0.34 |
4 | −2.842 | (−5.003, −0.68) | 0.01 |
Measured ordinally | −1.009 | (−1.68, −0.339) | 0.003 |
Chloride quartiles (fully adjusted) | |||
1 | Ref | Ref | |
2 | −0.626 | (−2.735, 1.484) | 0.56 |
3 | −1.696 | (−3.927, 0.536) | 0.14 |
4 | −3.378 | (−5.638, −1.118) | 0.004 |
Measured ordinally | −1.149 | (−1.858, −0.44) | 0.002 |