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Table 1 Effect of baicalin-lysozyme on renal function (blood urea nitrogen, serum creatinine and UPr) in rats with diabetic nephropathy

From: Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin

Group

N

BUN(mmol/L)

Scr(μmol/L)

UPr(mg/24h)

4 weeks

UPr(mg/24h)

8 weeks

Control

10

8.01±0.92

24.51±3.24

8.51±4.31

8.52±4.36

DN

15

16.97±3.63**

52.58±2.33**

30.98±12.66**

43.53±12.51***

DN/B

10

12.73±0.67##

43.77±1.73##

21.19±8.96*

19.01±9.91##

DN/B+L

10

10.81±0.61##$$

32.11±4.64##$$

15.66±10.36#

17.86±6.21##

  1. Data are presented as the mean ± standard deviation **P < 0.01 vs. the control group. #P < 0.05, ##P < 0.01 vs. the DN group. $$P < 0.01 vs. the control group