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Table 2 Outcomes of most recent transplant in patients treated with eculizumab prophylaxis pre-transplant versus patients not treated with eculizumab prophylaxis pre-transplant

From: Ten-year outcome of Eculizumab in kidney transplant recipients with atypical hemolytic uremic syndrome– a single center experience

Variable

Eculizumab prophylaxis (10 patients)

No eculizumab prophylaxis (9 patients)

p-value

Follow-up post-transplant, median years (range)

3.48 (0.36–7.21)

3.80 (1.30–14.70)

0.33

aHUS recurrence

0 (0%)

2 (22%)

0.15

Graft outcome

 Median creatinine, mg/dL (range)

1.3 (0.9–2.0)

1.1 (0.7 to 2.1)

0.46

 Median eGFR, ml/min/m2 (range)

55 (43–76)

61 (32–92)

0.55

 Hemodialysis, (n)

1 (10%)

4 (44%)

0.09

 Death, (n)

0 (0%)

0 (0%)

  1. aHUS atypical haemolytic uremic syndrome, eGFR estimated glomerular filtration rate