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Table 1 Comparison of baseline characteristics between patients with urological malignancy and no malignancy (total and matched sample)

From: Associations of urological malignancies with renal progression and mortality in advanced chronic kidney disease: a propensity-matched cohort study

  

Total sample

   

Matched sample

  

Variable

Total (2637)

Urological malignancy (UM) (160)

No malignancy (NM) (2477)

p-Value

UM vs NM

Total (640)

Urological malignancy (UM) (160)

No malignancy (NM) (480)

p-Value

UM vs NM

Age, years

67 (55–75.5)

72.5 (66.6–77.4)

66.5 (54.3–75.3)

< 0.001

72.5 (66.6–77.5)

72.5 (66.6–77.4)

72.4 (66.6–77.5)

0.97

Gender, male

1652 (62.6)

138 (86.3)

1514 (61.1)

< 0.001

550 (85.9)

138 (86.3)

412 (85.8)

0.90

Caucasian

2524 (95.7)

159 (99.4)

2365 (95.5)

0.02

638 (99.7)

159 (99.4)

479 (99.8)

0.41

Smoking

1719 (67.2)

116 (72.5)

1603 (64.7)

0.04

478 (74.7)

116 (72.5)

362 (75.4)

0.46

Alcohol

1236 (46.87)

77 (48.1)

1159 (46.79)

0.74

315 (49.2)

77 (48.1)

238 (49.6)

0.75

BMIa, kg/m2

28.1 (24.7–32.6)

28.1 (25.7–32.3)

28.1 (24.6–32.6)

0.55

28.1 (25–32)

28 (25.7–32.3)

28.2 (24.9–32)

0.48

Systolic BP, mmHg

138 (124–152)

140 (130–154)

138 (123–152)

0.08

140 (128–155)

140 (130–154)

140 (127–155)

0.92

Diastolic BP, mmHg

75 (66–80)

75.5 (66–82)

75 (66–80)

0.26

72 (65–80)

75 (66–82)

72 (64–80)

0.02

Hypertension

2397 (90.9)

140 (87.5)

2257 (91.1)

0.12

579 (90.5)

140 (87.5)

439 (91.5)

0.14

DM

866 (32.8)

53 (33.1)

813 (32.8)

0.94

244 (38.1)

53 (33.1)

191 (39.8)

0.13

IHD

492 (18.65)

34 (21.3)

458 (18.5)

0.39

46 (7.2)

34 (21.3)

112 (23.3)

0.59

MI

414 (15.7)

33 (20.6)

381 (15.4)

0.08

150 (23.4)

33 (20.9)

117 (24.4)

0.33

CCF

454 (17.2)

25 (15.6)

429 (17.3)

0.58

128 (20)

25 (15.8)

103 (21.5)

0.11

CVA

214 (8.1)

16 (10)

198 (7.99)

0.37

66 (10.3)

16 (10)

50 (10.4)

0.88

PVD

347 (13.2)

18 (11.3)

329 (13.3)

0.46

106 (16.6)

18 (11.4)

68 (14.2)

0.35

COPD

478 (18.1)

19 (11.8)

459 (18.5)

0.03

113 (17.6)

19 (12.1)

94 (19.6)

0.03

CLD

79 (2.9)

1 (0.63)

78 (3.1)

0.07

12 (1.87)

1 (0.63)

11 (2.29)

0.18

RAS blocker

1618 (61.4)

70 (43.8)

1548 (62.5)

< 0.001

355 (55.5)

70 (44.3)

285 (59.3)

0.001

Statin

1545 (58.6)

95 (59.4)

1450 (58.5)

0.84

415 (64.8)

95 (59.4)

320 (66.6)

0.09

ESA

340 (12.9)

14 (8.8)

326 (13.2)

0.11

84 (13.1)

14 (8.9)

70 (14.6)

0.06

Hb, g/L

123 (112–136)

124 (113–137)

123 (112–135)

0.67

123 (112–135)

124 (113–137)

123 (112–135)

0.57

ALP, Units/L

82 (65–103)

83 (66–100)

81 (65–103)

0.67

82 (66–102)

83 (66–101)

81 (66–102)

0.64

Calcium, mmol/L

2.30 (2.21–2.39)

2.31 (2.22–2.37)

2.30 (2.21–2.39)

0.91

2.30 (2.20–2.37)

2.31 (2.22–2.37)

2.30 (2.20–2.37)

0.28

Phosphate, mmol/L

1.12 (0.97–1.28)

1.09 (0.93–1.26)

1.12 (0.97–1.29)

0.04

1.07 (0.94–1.25)

1.09 (0.93–1.26)

1.07 (0.94–1.25)

0.96

uPCRb, g/mol

31 (13–107)

32.6 (12.9–93.4)

31.33 (13.04–107.7)

0.63

25.3 (12.5–85.3)

32.6 (12.9–88.2)

24.4 (12.4–82.8)

0.37

Creatinine, micromol/L

181 (135–256)

197 (151–286)

179 (135–254)

0.004

190 (145–274.7)

197 (151–286)

189 (144–272)

0.25

eGFR, mL/min/1.73m2

30 (20–42.9)

27.7 (17.5–39.1)

30.3 (19.8–43.2)

0.03

28.6 (18.1–39.8)

27.75 (17.5–39.1)

28.8 (18.5–40.1)

0.41

  1. BMI body mass index, BP blood pressure (mm of Hg), DM diabetes mellitus, IHD ischemic heart disease, MI myocardial infarction, CCF congestive cardiac failure, CVA cerebrovascular accident, PVD peripheral vascular disease, COPD chronic obstructive pulmonary disease, CLD chronic liver disease, RAS renin-angiotensin system, ESA erythropoietin stimulating agents, Hb haemoglobin, ALP alkaline phosphatase, uPCR urine protein creatinine ratio, eGFR estimated glomerular filtration rate calculated by CKD-EPI equation. Continuous variables are expressed as median (interquartile range) and p-Value by Mann-Whitney U test
  2. Categorical variables are expressed as number (%) and p-Value by Chi-Square test
  3. aBMI missing in 469 of 2477 of total sample and in 112 of 640 of matched sample
  4. bMissing uPCR values in 265 patients of total sample and 66 patients in matched sample