Total sample | Matched sample | |||||||
---|---|---|---|---|---|---|---|---|
Variable | Total (2637) | Urological malignancy (UM) (160) | No malignancy (NM) (2477) | p-Value UM vs NM | Total (640) | Urological malignancy (UM) (160) | No malignancy (NM) (480) | p-Value UM vs NM |
Age, years | 67 (55–75.5) | 72.5 (66.6–77.4) | 66.5 (54.3–75.3) | < 0.001 | 72.5 (66.6–77.5) | 72.5 (66.6–77.4) | 72.4 (66.6–77.5) | 0.97 |
Gender, male | 1652 (62.6) | 138 (86.3) | 1514 (61.1) | < 0.001 | 550 (85.9) | 138 (86.3) | 412 (85.8) | 0.90 |
Caucasian | 2524 (95.7) | 159 (99.4) | 2365 (95.5) | 0.02 | 638 (99.7) | 159 (99.4) | 479 (99.8) | 0.41 |
Smoking | 1719 (67.2) | 116 (72.5) | 1603 (64.7) | 0.04 | 478 (74.7) | 116 (72.5) | 362 (75.4) | 0.46 |
Alcohol | 1236 (46.87) | 77 (48.1) | 1159 (46.79) | 0.74 | 315 (49.2) | 77 (48.1) | 238 (49.6) | 0.75 |
BMIa, kg/m2 | 28.1 (24.7–32.6) | 28.1 (25.7–32.3) | 28.1 (24.6–32.6) | 0.55 | 28.1 (25–32) | 28 (25.7–32.3) | 28.2 (24.9–32) | 0.48 |
Systolic BP, mmHg | 138 (124–152) | 140 (130–154) | 138 (123–152) | 0.08 | 140 (128–155) | 140 (130–154) | 140 (127–155) | 0.92 |
Diastolic BP, mmHg | 75 (66–80) | 75.5 (66–82) | 75 (66–80) | 0.26 | 72 (65–80) | 75 (66–82) | 72 (64–80) | 0.02 |
Hypertension | 2397 (90.9) | 140 (87.5) | 2257 (91.1) | 0.12 | 579 (90.5) | 140 (87.5) | 439 (91.5) | 0.14 |
DM | 866 (32.8) | 53 (33.1) | 813 (32.8) | 0.94 | 244 (38.1) | 53 (33.1) | 191 (39.8) | 0.13 |
IHD | 492 (18.65) | 34 (21.3) | 458 (18.5) | 0.39 | 46 (7.2) | 34 (21.3) | 112 (23.3) | 0.59 |
MI | 414 (15.7) | 33 (20.6) | 381 (15.4) | 0.08 | 150 (23.4) | 33 (20.9) | 117 (24.4) | 0.33 |
CCF | 454 (17.2) | 25 (15.6) | 429 (17.3) | 0.58 | 128 (20) | 25 (15.8) | 103 (21.5) | 0.11 |
CVA | 214 (8.1) | 16 (10) | 198 (7.99) | 0.37 | 66 (10.3) | 16 (10) | 50 (10.4) | 0.88 |
PVD | 347 (13.2) | 18 (11.3) | 329 (13.3) | 0.46 | 106 (16.6) | 18 (11.4) | 68 (14.2) | 0.35 |
COPD | 478 (18.1) | 19 (11.8) | 459 (18.5) | 0.03 | 113 (17.6) | 19 (12.1) | 94 (19.6) | 0.03 |
CLD | 79 (2.9) | 1 (0.63) | 78 (3.1) | 0.07 | 12 (1.87) | 1 (0.63) | 11 (2.29) | 0.18 |
RAS blocker | 1618 (61.4) | 70 (43.8) | 1548 (62.5) | < 0.001 | 355 (55.5) | 70 (44.3) | 285 (59.3) | 0.001 |
Statin | 1545 (58.6) | 95 (59.4) | 1450 (58.5) | 0.84 | 415 (64.8) | 95 (59.4) | 320 (66.6) | 0.09 |
ESA | 340 (12.9) | 14 (8.8) | 326 (13.2) | 0.11 | 84 (13.1) | 14 (8.9) | 70 (14.6) | 0.06 |
Hb, g/L | 123 (112–136) | 124 (113–137) | 123 (112–135) | 0.67 | 123 (112–135) | 124 (113–137) | 123 (112–135) | 0.57 |
ALP, Units/L | 82 (65–103) | 83 (66–100) | 81 (65–103) | 0.67 | 82 (66–102) | 83 (66–101) | 81 (66–102) | 0.64 |
Calcium, mmol/L | 2.30 (2.21–2.39) | 2.31 (2.22–2.37) | 2.30 (2.21–2.39) | 0.91 | 2.30 (2.20–2.37) | 2.31 (2.22–2.37) | 2.30 (2.20–2.37) | 0.28 |
Phosphate, mmol/L | 1.12 (0.97–1.28) | 1.09 (0.93–1.26) | 1.12 (0.97–1.29) | 0.04 | 1.07 (0.94–1.25) | 1.09 (0.93–1.26) | 1.07 (0.94–1.25) | 0.96 |
uPCRb, g/mol | 31 (13–107) | 32.6 (12.9–93.4) | 31.33 (13.04–107.7) | 0.63 | 25.3 (12.5–85.3) | 32.6 (12.9–88.2) | 24.4 (12.4–82.8) | 0.37 |
Creatinine, micromol/L | 181 (135–256) | 197 (151–286) | 179 (135–254) | 0.004 | 190 (145–274.7) | 197 (151–286) | 189 (144–272) | 0.25 |
eGFR, mL/min/1.73m2 | 30 (20–42.9) | 27.7 (17.5–39.1) | 30.3 (19.8–43.2) | 0.03 | 28.6 (18.1–39.8) | 27.75 (17.5–39.1) | 28.8 (18.5–40.1) | 0.41 |