Skip to main content

Table 2 Comparison of mortality and renal outcomes between patients with urological malignancy and no malignancy in both total and matched sample

From: Associations of urological malignancies with renal progression and mortality in advanced chronic kidney disease: a propensity-matched cohort study

 

Total sample

   

Matched sample

  

Variable

Total (2637)

Urological malignancy (160)

No malignancy (2477)

p-Value

Urological malignancy (160)

No malignancy (480)

p-Value

Follow up, months

48 (25.5–79)

40.6 (23.4–69.6)

48.6 (25.6–79.5)

0.02

41.3 (23.7–72.7)

47.4 (25.8–77.8)

0.22

All-cause mortality

905 (34.3)

70 (43.75)

835 (33.7)

0.01

70 (43.8)

230 (47.9)

0.36

1st Cause death (Malignancy)

11/476 (2.3)

11/40 (27.5)

0/436 (0)

< 0.001a

11/40 (27.5)

0/111

< 0.001a

1st Cause death (CVD)

179/476 (37.6)

7/40 (17.5)

172/436 (39.4)

0.006

7/40 (17.5)

53/111 (47.7)

< 0.001

1St Cause death (Infection)

142/476 (29.8)

10/40 (25)

132/436 (30.3)

0.49

10/40 (25)

29/111 (26.1)

0.89

1st Cause death (ESRD)

55/476 (11.6)

4/40 (10)

51/436 (11.7)

1.00a

4/40 (10)

9/111 (8.1)

0.75a

Age at death, years

78.7 (72–84.4)

79.4 (73–83.8)

78.6 (72–84.4)

0.50

78.8 (72.9–83.7)

79.4 (74.5–83.6)

0.56

ESRD

777 (29.5)

45 (28.1)

732 (29.5)

0.70

45 (28.1)

131 (27.3)

0.84

RRT

568 (21.5)

28 (17.5)

540 (21.8)

0.20

28 (17.7)

72 (15)

0.45

NFCVE

251 (9.5)

17 (10.6)

234 (9.4)

0.24

17 (10.6)

59 (12.29)

0.57

Rate of decline of eGFR (eGFR slope)

mL/min/1.73m2/year

 

−1.05 (−2.5 to 0.52)

−1.25 (−3.27 to 0.51)

0.31

−1.05 (−2.5 to 0.52)

−0.88 (− 2.3 to 0.61)

0.58

  1. Cause of death represents 1a cause of death in death certificate. Cause of death available only in 476/905 patients of the total sample and 151/300 patients of the matched sample. CVD- cardiovascular disease, RRT- renal replacement therapy, ESRD- end-stage renal disease, NFCVE- non-fatal cardiovascular events
  2. Continuous variables are expressed as median (interquartile range) and p-Value by Mann-Whitney U test
  3. Categorical variables are expressed as number (%) and p-Value by Chi-square test
  4. eGFR -estimated glomerular filtration rate calculated by CKD-EPI equation
  5. eGFR slope was calculated on 2459/2637 patients in total sample and 593/640 patients in matched sample with three or more eGFRs
  6. ap-Value by Fisher exact test