Fig. 3From: Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in ratsBBG reduces the pool of myofibroblasts and collagen synthesis in UUO. a Graphical representation of α-SMA surface density in renal cortex. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. # p < 0.05 vs UUO-V and both SHAM groups. b Representative immunostaining of the renal cortex from UUO-V group and c UUO-BBG group. d Graphical representation of α-SMA surface density in renal medulla. The graphic shows aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. e Representative immunostaining of the renal medulla from UUO-V group and f UUO-BBG group. g Graphical representation of HSP-47 surface density in renal cortex. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. h Representative immunostaining of the renal cortex from UUO-V group and i UUO-BBG group. j Graphical representation of HSP-47 surface density in renal medulla. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. k Representative immunostaining of the renal medulla from UUO-V group and l UUO-BBG group. All pictures of the sham control groups are shown in the supplementary material. Bar = 100 μm in all figuresBack to article page