Table 3 Medications with potentially inappropriate prescribing
From: Quality use of medicines in patients with chronic kidney disease
Medications with potentially inappropriate dose | Patients prescribed N (%) | Patients with inappropriately high dose drug N (%) | Medications potentially contraindicated | Patients prescribed N (%) | Patients with potentially contraindicated medication N (%) |
|---|---|---|---|---|---|
Antidiabetic Medications | Antidiabetic Medications | ||||
Vildagliptin | 355 (1.2) | 274 (77.2) | Dapagliflozin | 296 (1.0) | 245 (82.8) |
Saxagliptin | 205 (0.7) | 117 (57.1) | Acarbose | 81 (0.3) | 12 (14.8) |
Sitagliptin | 1534 (5.3) | 742 (48.4) | Exenatide | 313 (1.1) | 18 (5.8) |
Metformin | 8046 (28.0) | 2885 (35.9) | Metformin | 8046 (28.0) | 37 (0.5) |
Alogliptin | 17 (0.1) | 5 (29.4) | Anticoagulant Medications | ||
Lipid Lowering Medications | Rivaroxaban | 1230 (4.3) | 99 (8.0) | ||
Fenofibrate | 1939 (6.7) | 1346 (69.4) | Dabigatran | 492 (1.7) | 34 (6.9) |
Rosuvastatin | 8529 (29.7) | 525 (6.2) | Apixaban | 938 (3.3) | 40 (4.3) |
Antihypertensive Medications | Cardiovascular Medications | ||||
Atenolol | 4832 (16.8) | 1849 (38.3) | Moxonidine | 1675 (5.8) | 447 (26.7) |
Moxonidine | 1675 (5.8) | 43 (2.6) | Spironolactone | 3050 (10.6) | 665 (21.8) |
Antiarrhythmics | Bisphosphonates | ||||
Digoxin | 2567 (8.9) | 24 (0.9) | Alendronate | 791 (2.8) | 251 (31.7) |
Anticoagulant Medications | Risedronate | 619 (2.2) | 118 (19.1) | ||
Rivaroxaban | 1230 (4.3) | 237 (19.3) | Others | ||
Dabigatran | 492 (1.7) | 39 (7.9) | Teriparatide | 7 (0.0) | 2 (28.6) |
Bisphosphonates | Strontium | 205 (0.7) | 43 (21.0) | ||
Clodronate | 10 (0.03) | 5 (50) | Dextropropoxyphene | 105 (0.4) | 33 (31.4) |
Zoledronate | 24 (0.1) | 1 (4.2) | Pramipexole | 523 (1.8) | 100 (19.1) |
Antihistamines | Probenecid | 115 (0.4) | 1 (0.9) | ||
Nizatidine | 283 (1.0) | 170 (60.1) | |||
Cimetidine | 15 (0.1) | 3 (20.0) | |||
Cetirizine | 261 (0.9) | 50 (19.2) | |||
Psychotropic Medications | |||||
Paliperidone | 6 (0.02) | 4 (66.7) | |||
Desvenlafaxine | 572 (2.0) | 70 (12.2) | |||
Duloxetine | 846 (2.9) | 87 (10.3) | |||
Venlafaxine | 1050 (3.7) | 47 (4.5) | |||
Varenicline | 150 (0.5) | 6 (4.0) | |||
Neurological Medications | |||||
Tramadol | 571 (2) | 67 (11.7) | |||
Gabapentin | 341 (1.2) | 30 (8.8) | |||
Levetiracetam | 179 (0.6) | 9 (5) | |||
Pregabalin | 4642 (16.2) | 190 (4.1) | |||
Pramipexole | 523 (1.8) | 3 (0.6) | |||
Others | |||||
Tolterodine | 20 (0.1) | 2 (10.0) | |||
Solifenacin | 458 (1.6) | 21 (4.6) | |||