Table 1 Laboratory investigations prior to Cesarean section to the intensive care unit (ICU) and to our unit
From: Severe HELLP syndrome masquerading as thrombocytopenic thrombotic purpura: a case report
Variable | Normal range | Prior to Cesarean | Admission to the ICU | Admission to our unit |
|---|---|---|---|---|
Hematology and coagulation assays | ||||
Hemoglobin (g/dL) | 12–16 | 11.7 | 12.6 | 6 |
White cell count (per μL) | 4500–10,000 | 21,000 | 27,600 | 30,000 |
Differential count (%) | ||||
Neutrophils | 40–70 | 76 | 76.7 | 83 |
Others | 30–70 | 24.3 | 17 | |
Platelet count (per μL) | 150,000–400,000 | 160,000 | 155,000 | 53,000 |
Fibrinogen (g/liter) | 2–6 | 2.41 | 2 | 4.59 |
Schizocytes (%) | < 1 | 0 | Not specified | 2 |
Prothrombin time (%) | 70–110 | 85 | 61 | 58 |
Factor V (%) | 70–120 | 75 | 24 | 70 |
Activated partial thromboplastin time ratio | 0.8–1.2 | 1.2 | 1.21 | 1.31 |
D-dimers | < 500 | > 20,000 | ||
Renal analysis | ||||
Creatinine (mg/dL) | 0.6–1.5 | 1.1 | 1.56 | 3.7 |
Blood urea nitrogen (mg/dL) | 8–25 | 14 | 38.8 | |
Hepatic analysis | ||||
Albumin (g/L) | 35–50 | 25 | 21 | |
Lactate dehydrogenase (U/L) | 125–250 | 5000 | 7820 | |
Haptoglobin (g/L) | 0.2–0.4 | 0.2 | < 0.08 | |
Aspartate aminotransferase (U/L) | < 35 | Hemolysis | 1749 | |
Alanine aminotransferase (U/L) | < 45 | 500 | 833 | |
Alkaline phosphatase (U/L) | < 115 | 229 | 283 | |
Gamma glutamyl transpeptidase (U/L) | < 45 | 168 | 212 | |
Bilirubin total/conjugate (mg/dL) | 0.3–1.9 / 0–0.3 | 13.7 / 8.9 | 40 / 28.2 | |
Arterial lactate (mmol/L) | 0–2 | 1.9 | 2.2 | |
TMA exploration | ||||
ADAMTS13 activity (%) | 50–150 | < 5% | ||
IgG anti-ADAMTS13 | Negative | |||
Coombs test | Negative | Negative | ||
HIV test | Negative | |||
C3 (g/L) | 0.9–1.8 | 0.56 | ||
C4 (g/L) | 0.1–0.4 | 0.06 | ||
Antinuclear and anti-DNA antibodies | Negative | |||
Factor H (%) | 65–140 | 106 | ||
Factor I (%) | 70–130 | 125 | ||
Factor H autoantibody | Negative | |||
Antiphospholipid antibodiesa | Negative | |||