Sedentary behaviour, physical activity, and renal function in older adults: isotemporal substitution modelling

BMC Nephrology

Table 2 Single factor, partition, and isotemporal substitution models for renal function represented by eGFR

Models		Sedentary behaviour	LPA	MVPA	R-Square
Models		β (95% CI)	β (95% CI)	β (95% CI)	R-Square
Single factor model^a,b	1	– 3.31 (− 5.17,– 1.45)^**			0.262^**
	2		3.62 (1.04,6.19)^*		0.242^**
	3			7.06 (2.79,11.34)^*	0.255^**
Partition model^a	4	– 0.81 (− 1.77,0.16)	1.45 (− 1.33,4.24)	4.68 (− 0.04,9.40)	0.267^**
Isotemporal substitution model^a,b	5	Dropped	2.26 (− 0.53,5.05)	5.49 (0.81,10.17)^*	0.267^**
	6	– 2.26 (− 5.05,0.53)	Dropped	3.23 (− 3.13,9.60)	0.267^**
	7	– 5.49 (− 10.17,– 0.81)^*	– 3.23 (− 9.60,3.13)	Dropped	0.267^**

^aAll models adjusted for age, sex, body mass index, systolic blood pressure, heart rate, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, fasting blood glucose, albuminuria, medication use (antihypertensive, lipid-lowering, and hypoglycaemic agents), and current smoking. ^bsingle factor and isotemporal substitution models were also adjusted for total waking time. Regression coefficients (β) correspond to a 30 min/day of each behaviour. ^**p < 0.001, ^*p < 0.05. LPA, light-intensity physical activity; MVPA, moderate- to vigorous-intensity physical activity

ISSN: 1471-2369