Acute kidney disease and acute kidney injury biomarkers in coronary care unit patients

BMC Nephrology

Table 2 Logistic regression analysis for AKD according to baseline prognostic factors

Parameter	Beta Coefficient	Standard error	Odds ratio (95% CI)	p-value
Univariable logistic regression
Age	0.037	0.010	1.038(1.018–1.057)	< 0.001
Hemoglobin	−0.321	0.059	0.725(0.646–0.814)	< 0.001
Body temperature	0.327	0.149	1.387(1.036–1.858)	0.028
Respiratory rate	0.077	0.022	1.080(1.034–1.128)	0.001
Serum creatinine 0–24 h	0.821	0.283	2.272(1.306–3.954)	0.004
Serum creatinine 24–48 h	1.605	0.561	4.980(1.660–14.940)	0.004
Serum creatinine 48–72 h	0.774	0.261	2.168(1.301–3.614)	0.003
hsCRP	0.014	0.004	1.014(1.005–1.023)	0.002
Ejection fraction	−0.022	0.008	0.978(0.963–0.993)	0.004
BNP	0.001	0.000	1.001(1.001–1.002)	< 0.001
Albumin	−1.581	0.342	0.206(0.105–0.402)	< 0.001
Serum IL-18	0.003	0.001	1.003(1.002–1.005)	< 0.001
Serum NGAL	0.003	0.001	1.003(1.001–1.006)	0.009
Urine NGAL	0.006	0.003	1.007(1.001–1.012)	0.011
Serum CysC	0.000	0.000	1.000(1.000–1.001)	0.001
Multivariable logistic regression
Hemoglobin	−0.241	0.085	0.786(0.665–0.928)	0.004
Age	0.034	0.014	1.034(1.007–1.063)	0.014
Ejection fraction	−0.025	0.011	0.975(0.955–0.996)	0.021
Serum IL-18	0.002	0.001	1.002(1.000–1.004)	0.015

IL-18 Interleukin 18, NGAL Neutrophil gelatinase-associated lipocalin, CysC Cystatin C, hsCRP High sensitivity C-reactive protein, BNP B-type natriuretic peptide

ISSN: 1471-2369