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Fig. 7 | BMC Nephrology

Fig. 7

From: Repository corticotropin injection versus corticosteroids for protection against renal damage in a focal segmental glomerulosclerosis rodent model

Fig. 7

Podocyte and Glomerular Assessment in the 12-week PAN Model. a Saline EM image. Red arrows = podocyte effacement. b RCI 60 IU/kg EM image. Blue arrows = normal podocyte foot process structure. a, b Green * = capillary basement membrane; CL = capillary lumen; scale bar = 4 μM. c Group prevalence of podocyte effacement by EM analysis. *p < 0.05, Fisher’s exact test for group differences compared with saline, 2-tailed. d Total glomerular injury score. *p < 0.05, Kruskal-Wallis nonparametric ANOVA, Dunn’s post hoc test, comparing the RCI treatment groups with saline. Values are mean ± standard error of the mean. For all panels, naive samples are not shown because of low sample size. Abbreviations: ANOVA, analysis of variance; EM, electron microscopy; PAN, puromycin aminonucleoside; RCI, repository corticotropin injection

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