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Table 1 Baseline characteristics of the 8-week and 12-week PAN models

From: Repository corticotropin injection versus corticosteroids for protection against renal damage in a focal segmental glomerulosclerosis rodent model

Parameter

8-week PAN model

12-week PAN model

Mean ± SD

Naive

Saline

RCI 30 IU/kg/qod

MP 2 mg/kg/qd

Naive

Saline

RCI 10 IU/kg/qod

RCI 30 IU/kg/qod

RCI 60 IU/kg/qod

n

3

8

8

8

4

8

8

6

8

Body Weight (g)

220.2 ± 11.6

208.0 ± 7.0

207.0 ± 10.6

212.9 ± 7.0

177.1 ± 7.1

181.1 ± 5.7

178.7 ± 7.8

176.7 ± 4.6

176.9 ± 6.4

Urine Protein (mg/24 h)

2.8 ± 1.1

3.2 ± 1.5

2.9 ± 0.6

3.3 ± 1.2

1.7 ± 0.6

1.1 ± 0.4

1.0 ± 0.5

1.3 ± 1.0

1.1 ± 0.3

  1. No significant differences were observed between groups for mean weight or baseline urine protein
  2. Abbreviations: MP Methylprednisolone, PAN Puromycin aminonucleoside, RCI Repository corticotropin injection, SD Standard deviation, qod Every other day, qd Per day
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BMC Nephrology

ISSN: 1471-2369

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