| All patients (n = 221) | Ferritin ≥100 μg/L (n = 152) | Ferritin < 100 μg/L (n = 69) | P | ||
---|---|---|---|---|---|---|
hsCRP > 3 mg/L (n = 96) | hsCRP≤ 3 mg/L (n = 56) | hsCRP> 3 mg/L (n = 45) | hsCRP≤ 3 mg/L (n = 24) | |||
Ferritin, μg/L | 291.4 ± 334.1 | 435.3 ± 384.2 | 355.4 ± 266.1 | 42.1 ± 26.0 | 36.1 ± 24.1 | 0.000 |
Demographics | ||||||
 Age, years | 53.0 ± 14.1 | 55.0 ± 14.6 | 52.5 ± 13.0 | 52.5 ± 16.1 | 47.8 ± 10.8 | 0.308 |
 Male, n (%) | 122(55.5) | 63 (65.6) | 34 (60.7) | 22 (48.9) | 3 (12.5) | 0.000 |
 Body mass index, kg/m2 | 22.6 ± 4.6 | 21.9 ± 4.2 | 22.0 ± 4.7 | 22.5 ± 3.7 | 21.3 ± 3.9 | 0.377 |
Causes of ESKD, % (n) | ||||||
 Chronic glomerulonephritis | 93 (42.1) | 30 (31.3) | 32 (57.1) | 20 (44.4) | 11 (45.9) | 0.018 |
 Diabetes mellitus | 51 (23.1) | 21 (21.9) | 11 (19.6) | 13 (28.9) | 6 (25.0) | 0.716 |
 Hypertension | 31 (14.0) | 20 (20.8) | 3 (5.4) | 7 (15.6) | 1 (4.2) | 0.027 |
 Obstructive nephropathy | 18 (8.1) | 9 (9.4) | 3 (5.4) | 4 (8.9) | 2 (8.3) | 0.847 |
 Lupus nephritis | 17 (7.7) | 9 (9.4) | 3 (5.4) | 1 (2.2) | 4 (16.7) | 0.143 |
 Others | 11 (5.0) | 7 (7.2) | 4 (7.1) | 0 (0.0) | 0 (0) | 0.154 |
Deaths | ||||||
 All-cause death, % (n) | 50 (22.6) | 31 (32.3) | 8 (14.3) | 8 (17.8) | 3 (12.5) | 0.025 |
 Cardiovascular death, % (n) | 23 (10.4) | 15 (15.6) | 3 (5.3) | 3 (6.7) | 2 (8.3) | 0.163 |
Biochemical parameters | ||||||
 24 h Urine Amount, mL | 1366.8 ± 639.5 | 1326.5 ± 636.0 | 1371.9 ± 638.1 | 1347.0 ± 667.1 | 1427.8 ± 711.1 | 0.952 |
 SBP, mmHg | 156.0 ± 21.7 | 157.8 ± 20.5 | 153.0 ± 24.0 | 153.0 ± 23.9 | 159.0 ± 24.0 | 0.416 |
 DBP, mmHg | 87.8 ± 13.4 | 88.2 ± 12.5 | 86.5 ± 13.0 | 87.8 ± 14.8 | 89.1 ± 15.9 | 0.871 |
 Kt/V | 2.0 ± 0.6 | 2.0 ± 0.6 | 2.3 ± 1.0 | 2.0 ± 0.4 | 2.0 ± 0.4 | 0.739 |
 PET D/Pcr | 0.7 ± 0.1 | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.484 |
 BUN, mmol/L | 29.6 ± 12.6 | 29.7 ± 13.8 | 31.7 ± 12.0 | 27.2 ± 12.0 | 29.3 ± 9.4 | 0.377 |
 Creatinine, μmol/L | 790.6 ± 258.0 | 785.8 ± 282.0 | 807.2 ± 211.3 | 812.0 ± 253.2 | 742.9 ± 273.3 | 0.731 |
 eGFR, mL/min/1.73 m2 | 6.0 ± 2.6 | 6.4 ± 2.7 | 5.3 ± 2.2 | 5.6 ± 2.1 | 6.1 ± 3.4 | 0.271 |
 Phosphorus, mmol/L | 2.0 ± 0.6 | 2.1 ± 0.7 | 2.1 ± 0.6 | 2.0 ± 0.6 | 2.1 ± 0.5 | 0.854 |
 Calcium, mmol/L | 1.9 ± 0.3 | 1.9 ± 0.3 | 2.0 ± 0.3 | 1.9 ± 0.3 | 2.0 ± 0.2 | 0.431 |
 Cholesterol, mmol/L | 4.7 ± 1.5 | 4.7 ± 1.7 | 4.7 ± 1.3 | 4.6 ± 1.2 | 5.4 ± 1.6 | 0.153 |
 Triglyceride, mmol/L | 1.7 ± 1.0 | 1.6 ± 1.0 | 1.7 ± 0.9 | 1.8 ± 1.1 | 1.7 ± 1.1 | 0.787 |
 LDL-C, mmol/L | 2.9 ± 1.1 | 2.9 ± 1.2 | 2.9 ± 1.0 | 3.1 ± 1.1 | 3.1 ± 1.1 | 0.745 |
 HDL-C, mmol/L | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.3 ± 0.4 | 0.067 |
 apolipoproteinA, g/L | 1.0 ± 0.2 | 1.0 ± 0.3 | 1.1 ± 0.2 | 1.0 ± 0.2 | 1.1 ± 0.3 | 0.319 |
 Uric acid, μmol/L | 538.0 ± 140.2 | 552.0 ± 138.9 | 550.0 ± 126.6 | 493.2 ± 136.2 | 539.5 ± 169.8 | 0.132 |
 hs-CRP, mg/L | 21.0 ± 36.3 | 37.1 ± 43.2 | 0.7 ± 0.1 | 20.3 ± 35.0 | 1.1 ± 0.8 | 0.000 |
 Albumin, g/L | 32.7 ± 5.4 | 31.9 ± 5.2 | 34.3 ± 6.0 | 32.3 ± 4.6 | 33.0 ± 5.7 | 0.067 |
 Prealbumin, g/L | 0.3 ± 0.2 | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.4 ± 0.3 | 0.3 ± 0.1 | 0.145 |
 Hemoglobin, g/L | 82.0 ± 20.0 | 78.9 ± 21.6 | 81.0 ± 17.6 | 84.4 ± 20.8 | 84.1 ± 15.8 | 0.427 |
 iPTH, pg/mL | 349.0 ± 292.2 | 307.2 ± 281.3 | 368.2 ± 238.2 | 382.9 ± 368.8 | 391.7 ± 295.6 | 0.587 |
 TAST, % | 0.3 ± 0.2 | 0.3 ± 0.2 | 0.4 ± 0.2 | 0.3 ± 0.2 | 0.4 ± 0.2 | 0.407 |
 Fe (iron), μmol/L | 48.1 ± 44.1 | 48.4 ± 49.8 | 50.7 ± 42.0 | 44.4 ± 33.0 | 42.5 ± 40.4 | 0.909 |