Association of urinary non-albumin protein with the different urinary marker for glomerular and tubular damage in patients with type 2 diabetes

Table 2 Correlation of non-albumin protein to creatinine ratio with clinical, anthropometric and biochemical characteristics; and other urinary markers in type 2 diabetes subjects

Variables	Total patients (424)		Group 1 (269)		Group 2 (155)
	r	p	r	p	r	p
Age years	0.082	0.113	0.044	0.480	0.049	0.598
BMI, kg/m²	0.042	0.418	0.101	0.111	−0.021	0.826
Duration of diabetes, years	0.138	0.008	0.158	0.011	0.101	0.276
SBP, mmHg	0.136	0.008	0.224	<0.001	0.028	0.766
DBP, mmHg	−0.007	0.889	0.193	0.002	−0.179	0.052
FBS, mg/dL	0.058	0.263	0.056	0.377	0.002	0.980
HbA1c, %	0.191	<0.001	0.212	0.001	0.136	0.141
Total cholesterol, mg/dL	0.079	0.128	0.084	0.180	−0.033	0.727
LDL, mg/dL	−0.002	0.966	0.047	0.456	−0.074	0.432
HDL, mg/dL	0.044	0.394	0.099	0.116	−0.026	0.778
Triglycerides, mg/dL	0.061	0.244	0.022	0.726	0.012	0.898
eGFR, mL/min/1.73 m²	−0.411	< 0.001	− 0.151	0.015	− 0.545	< 0.001
ACR, mg/g	0.624	<0.001	0.411	<0.001	0.635	<0.001
PCR, mg/g	0.873	<0.001	0.850	<0.001	0.867	<0.001
Transferrin/Cr, μg/g	0.439	<0.001	0.276	<0.001	0.447	<0.001
RBP/Cr, μg/g	0.555	<0.001	0.516	<0.001	0.539	<0.001
NGAL/Cr, μg/g	0.390	<0.001	0.241	<0.001	0.466	<0.001

Group 1,eGFR ≥60 mL/min/1.73 m²; Group 2, eGFR <60 mL/min/1.73 m²; BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBS Fasting blood sugar, HbA1c Hemoglobin A1c, LDL Low-density lipoprotein, HDL High-density lipoprotein, eGFR Estimated glomerular filtration rate, ACR Albumin-to-creatinine ratio, PCR Total protein-to-creatinine ratio, Transferrin/Cr transferrin-to-creatinine ratio; RBP/Cr Retinol binding protein-to-creatinine ratio, NGAL/Cr Neutrophil gelatinase-associated lipocalin-to-creatinine ratio, r; coefficients of correlation, p < 0.05 was considered significant

ISSN: 1471-2369