Table 2 Allografts’ characteristics
FSGS n = 49 | No FSGS n = 51 | p-value | |
|---|---|---|---|
Type of donation | DKTa: 15/49 (30.5%) | DKT: 9/51 (17.5%) | 0.1291 |
LKTb: 34/49 (69.5%) | LKT: 42/51 (82.5%) | ||
Induction immunosuppression | rATGc: 42/49 (86%) | rATG: 41/51 (80%) | 0.4787 |
Other: 7/49 (14%) | Other: 10/51 (20%) | ||
Maintenance immunosuppression | Standardd: 44/49 (90%) | Standard: 50/51 (98%) | 0.0827 |
Non standard: 5/49 (10%) | Non standard: 1/51 (2%) | ||
Previous one renal transplant | 14/49 (28.5%) | 19/51 (37%) | 0.3559 |
Previous two or more renal transplants | 10/49 (20%) | 5/51 (10%) | 0.1376 |
Median Cr at time of biopsy (IQR) | 1.50 (1.10–1.98) | 1.20 (1.00–1.90) | 0.1770 |
Median eGFR at time of biopsy (IQR) | 49 (36.5–63.5) | 49 (34–65) | 0.7113 |
Median proteinuria at time of biopsy (IQR) | 1.65 (0.41–2.99) | 0.175 (0.07–0.37) | < 0.00001 |
Presence of donor specific antibodies | Negative 14/49 (28.5%) | Negative 19/51 (37%) | 0.5697 |
Low positive 11/49 (22.5%) | Low positive 12/51 (23%) | ||
Positive 24/49 (49%) | Positive 20/51 (40%) | ||
Biopsy proven ABMRf | 15/49 (30.5%) | 13/51 (25.5%) | 0.5684 |
Biopsy proven CMRg | 5/49 (10%) | 4/51 (8%) | 0.6800 |
Biopsy proven AMR and CMR (mixed) | 1/49 (2%) | 2/51 (4%) | 0.5815 |