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Table 1 Characteristics of the 4 patients with a kidney injury related to Parvovirus B19 primary infection. (NA: not available)

From: Parvovirus B19 infection and kidney injury: report of 4 cases and analysis of immunization and viremia in an adult cohort of 100 patients undergoing a kidney biopsy

  Case #1 Case #2 Case #3 Case #4
Gender Female Female Male Female
Age (years) 42 42 28 19
Past medical history None None None Sickle cell disease
Clinical examination Diffuse edema and pleural effusion Acute nephritic syndrome, fever, rash Fever, diarrhea, pallor Edema, pallor
Serum creatinine (mg/dL) 1.17 1.33 6.14 1
Serum albumin (g/dL) 2.5 3.3 3.4 2,4
Proteinuria (g/24 h) 9.6 1 0.8 3,5
Hemoglobin (g/dL) 10.7 8.4 11.9 6,3
Reticulocytes (G/L) 35 82 4 136
C3 level (g/L) low low normal normal
C4 level (g/L) normal normal normal normal
CH50 (%) low low normal normal
Antinuclear antibodies negative negative NA negative
ANCA NA negative NA NA
Cryoglobulinemia mixed 2a mixed 2b mixed 2 NA
VHC antibodies negative negative negative NA
PVB19 IgG antibodies positive positive positive positive
PVB19 IgM antibodies positive positive positive positive
PVB19 PCR: blood positive positive positive negative
PVB19 PCR: renal tissue NA positive NA negative
Kidney Biopsy Membrano-proliferative GN, full-house pattern Minimal change disease and acute tubular necrosis NA Membrano-proliferative GN, C3 deposits