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Table 2 Pathological findings at the time of biopsy in children with IgA nephropathy (n = 1243)

From: The correlation analysis between the Oxford classification of Chinese IgA nephropathy children and renal outcome - a retrospective cohort study

Pathology findings Values at renal biopsy
The number of glomeruli per biopsy 20.4 ± 4.7
MEST-C score % of total biopsies
M1 29
E1 35
S1 37
T1 23
T2 4.3
C1 44
C2 4.6
Deposition site of immunoglobulins % of total biopsies
Pure-mesangium 68
Mesangium+ capillary loop 32
Immunoglobulins deposits % of total biopsies
Glomerular IgG deposition 25
Glomerular IgM deposition 44
Glomerular C3 deposition 84
Glomerular C4 deposition 1.1
Intensity of IgA deposits a % of total biopsies
1+ 5.6
2+ 13
3+ 81
  1. Values are expressed as mean ± SD or number (percentage); The intensity of IgA deposits as determined via immunofluorescence microscopy was graded semi-quantitatively on a scale from 0 to 3+, where 0 no, 1 + = slight, 2 + = moderate, and 3 + = intense
  2. Abbreviations: M1 Mesangial hypercellularity>0.5, E1 Presence of endocapillary hypercellularity, S1 Presence of segmental glomerulosclerosis, T1 Tubular atrophy/ interstitial fibrosis 26–50% of cortical area, T2 Tubular atrophy/interstitial fibrosis≥50% of cortical area, C1 Crescents in at least one but < 25% of glomeruli, C2 Crescents in more than 25% of glomeruli