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Table 4 Univariate and multivariate Cox-proportional hazard analysis of variables associated with end-stage renal disease

From: Comparison of clinical features and outcomes between patients with early and delayed lupus nephritis

  Univariate analysis Multivariate analysis
Odds ratio 95% CI p-value Odds ratio 95% CI p-value
Age, years 1.046 1.007–1.086 0.021    
Female sex 1.648 0.215–12.638 0.631    
SLEDAI-2 K 0.915 0.791–1.057 0.227    
Complement 3, mg/dL 0.989 0.967–1.011 0.327    
Complement 4, mg/dL 0.971 0.897–1.051 0.470    
Anti-dsDNA (IU/mL) 0.998 0.995–1.001 0.183    
Spot urine P/Cr ratio 1.001 0.863–1.159 0.995    
WBC count (/μL) 1.000 0.999–1.000 0.900    
Platelet count (×1000/μL) 0.995 0.989–1.002 0.139    
Hemoglobin (g/dL) 0.601 0.455–0.795 < 0.001    
Lymphocyte count (/μL) 0.999 0.998–1.000 0.099    
ESR (mm/hr) 1.006 0.990–1.022 0.493    
CRP (mg/L) 1.015 1.002–1.028 0.028 1.021 1.006–1.037 0.007
Cr (mg/dL) 2.445 1.801–3.317 < 0.001 2.233 1.539–3.239 < 0.001
Albumin (g/dL) 0.620 0.306–1.259 0.186    
Activity index 1.058 0.959–1.167 0.261    
Chronicity index 1.581 1.199–2.083 0.001 1.475 1.042–2.090 0.029
Early lupus nephritis 0.830 0.295–2.337 0.725    
Delayed lupus nephritis 1.204 0.428–3.388 0.725    
  1. SLEDAI-2 K systemic lupus erythematosus disease activity index-2000, P/Cr protein/creatinine, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, Cr creatinine