BMC Nephrology

Table 4 Univariate and multivariate Cox-proportional hazard analysis of variables associated with end-stage renal disease

From: Comparison of clinical features and outcomes between patients with early and delayed lupus nephritis

	Univariate analysis			Multivariate analysis
	Odds ratio	95% CI	p-value	Odds ratio	95% CI	p-value
Age, years	1.046	1.007–1.086	0.021
Female sex	1.648	0.215–12.638	0.631
SLEDAI-2 K	0.915	0.791–1.057	0.227
Complement 3, mg/dL	0.989	0.967–1.011	0.327
Complement 4, mg/dL	0.971	0.897–1.051	0.470
Anti-dsDNA (IU/mL)	0.998	0.995–1.001	0.183
Spot urine P/Cr ratio	1.001	0.863–1.159	0.995
WBC count (/μL)	1.000	0.999–1.000	0.900
Platelet count (×1000/μL)	0.995	0.989–1.002	0.139
Hemoglobin (g/dL)	0.601	0.455–0.795	< 0.001
Lymphocyte count (/μL)	0.999	0.998–1.000	0.099
ESR (mm/hr)	1.006	0.990–1.022	0.493
CRP (mg/L)	1.015	1.002–1.028	0.028	1.021	1.006–1.037	0.007
Cr (mg/dL)	2.445	1.801–3.317	< 0.001	2.233	1.539–3.239	< 0.001
Albumin (g/dL)	0.620	0.306–1.259	0.186
Activity index	1.058	0.959–1.167	0.261
Chronicity index	1.581	1.199–2.083	0.001	1.475	1.042–2.090	0.029
Early lupus nephritis	0.830	0.295–2.337	0.725
Delayed lupus nephritis	1.204	0.428–3.388	0.725

SLEDAI-2 K systemic lupus erythematosus disease activity index-2000, P/Cr protein/creatinine, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, Cr creatinine

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