Skip to main content

Table 1 Characteristics of patients receiving LMWH compared to UFH in hemodialysis

From: Osteoporotic fracture rates in chronic hemodialysis and effect of heparin exposure: a retrospective cohort study

Covariates

LMWH

UFH

p value

n = 1426 (%)

n = 3370 (%)

Agea (years) ± SD

67.88 ± 13.7

66.57 ± 14.2

0.003

Sex (Female)

589 (41.3)

1316 (39.1)

0.14

Hemodialysis incidence

1090 (76.4)

2215 (65.7)

< 0.0001

Hospitalization in prior year

1117 (78.3)

2678 (79.5)

0.38

Comorbiditiesb

 Cardiovascular disease

757 (53.1)

1836 (54.5)

0.38

 Cerebrovascular disease

121 (8.5)

315 (9.4)

0.34

 Chronic pulmonary disease

324 (22.7)

711 (21.1)

0.21

 Chronic liver disease

72 (5.1)

213 (6.3)

0.09

 Congestive heart failure

473 (33.2)

1051 (31.2)

0.18

 Diabetes

796 (55.8)

1823 (54.1)

0.27

 Hyperlipidemia

876 (61.4)

2132 (63.3)

0.23

 Hypertension

1169 (82.0)

2614 (77.6)

0.001

 Malignancy

289 (20.3)

679 (20.2)

0.93

 Peripheral vascular disease

407 (28.5)

992 (29.4)

0.53

 Rheumatoid arthritis

22 (1.5)

66 (2.0)

0.33

 Osteoporosis

92 (6.5)

205 (6.1)

0.63

 Parathyroidectomy

0 (0.0)

10 (0.3)

0.04

 Prior fracture

34 (2.4)

100 (3.0)

0.26

Drug usec

 NSAIDs

743 (52.1)

1763 (52.3)

0.89

 Steroids

212 (14.9)

565 (16.8)

0.10

 Calcium

872 (61.2)

2121 (62.9)

0.24

 Vitamin D

801 (56.2)

1750 (51.9)

0.01

 Phosphorus chelating agents

914 (64.1)

2249 (66.7)

0.08

 Cinacalcet

14 (1.0)

18 (0.5)

0.08

  1. aAt index date
  2. bAt index date in the two years prior
  3. cAt index date in the six months prior
  4. Abbreviations: SD Standard deviation, NSAID Non-steroidal anti-inflammation drugs, LMWH Low Molecular Weight heparin, UFH Unfractionated heparin