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Table 2 values of percentages and absolute numbers of T cell subset during aging

From: Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients

  ALL Aged 20–45 Aged 46–59 Aged 60–69 Aged 70–79 Aged 80–89 P value
N = 446 N = 84 N = 128 N = 129 N = 63 N = 42
Cell subset percentage
 CD4+T cells %* 57.1(49.6,64.6) 55.5(49.2,60.4) 58.2 (52.3,67.0) 57.9(50.4,65.8) 54.6(47.6,63.2) 56.2(48.3,67.0) 0.02
 CD4+ TNAIVE %* 36.7(26.2,46.8) 43.5(34.0,53.1) 37.1(26.5,48.3) 34.9(26.2,45.5) 29.5(20.7,44.9) 32.9(20.1,45.3) < 0.001
 CD4+TCM%* 21.7(15.1,28.7) 17.0(12.4,25.7) 21.3(15.2,25.9) 23.5(15.4,31.2) 23.1(18.5,31.4) 22.6(15.3,29.4) 0.002
 CD4+TEM%* 33.2(25.4,42.3) 28.7(22.3,34.8) 32.8(25.4,42.0) 35.1(25.2,43.3) 37.9(26.2,45.6) 36.1(26.1,45.6) < 0.001
 CD4+TEMRA% 4.2(2.5,7.6) 4.8(2.8,8.9) 4.9(2.8,7.5) 4.3(2.5,7.9) 3.4(2.2,6.3) 3.6(2.0,6.2) 0.932
 CD8+T cells %* 34.6(28.5,41.3) 36.2(32.3,42.1) 32.7(26.9,40.3) 33.2(26.8,39.4) 36.1(30.3,46.3) 36.0(27.5,43.9) 0.003
 CD8+ TNAIVE % * 19.9(12.2,30.3) 37.1(28.4,52.5) 22.7(16.5,33.1) 15.5(13.0,24.9) 10.5(7.2,17.7) 9.5(5.3,15.4) < 0.001
 CD8+ TCM%* 2.8(1.7,4.5) 2.1(1.4,2.9) 2.7(1.7,4.3) 3.5(2.0,4.9) 3.1(1.7,4.9) 3.1(1.7,5.3) 0.001
 CD8 +TEM%* 22.5(15.5,30.9) 17.3(12.6,23.1) 22.0(16.1,30.2) 25.5(16.0,33.0) 27.1(17.2,36.2) 24.7(16.2,38.4) < 0.001
 CD8+TEMRA%* 49.7(37.0,60.3) 40.1(27.9,50.0) 48.1(34.1,58.1) 52.2(39.7,59.9) 57.9(43.3,69.8) 63.1(45.8,70.4) < 0.001
 CD4+Tcell /CD8+ T cell 1.64(1.21,2.25) 1.50(1.18,1.88) 1.76(1.31,2.49) 1.73(1.31,2.54) 1.56(1.01,2.02) 1.52(1.10,2.43) 0.051
Absolute cell number
 CD4+T cells (cells/μl)* 387(291,548) 500(367,636) 428(326,549) 369(279,524) 352(211,447) 345(264,411) < 0.001
 CD4+ TNAIVE (cells/μl)* 135(81,224) 226(148,292) 151(86,232) 124(84,186) 101(41,147) 104(56,175) < 0.001
 CD4+TCM (cells/μl) 85(54,126) 86(50,140) 84(55,125) 88(55,125) 79(54,130) 80(47,112) 0.324
 CD4+TEM (cells/μl) 129(86,187) 136(91,189) 139(88,190) 127(89,180) 115(83,172) 108(78,197) 0.487
 CD4+TEMRA (cells/μl)* 18(10,32) 25(11,46) 20(10,36) 16(10,28) 13(6,28) 13(7,20) 0.005
 CD8+T cells (cells/μl)* 236(162,355) 318(251,448) 226(163,353) 209(138,315) 217(159,326) 219(139,321) < 0.001
 CD8+ TNAIVE (cells/μl)* 44(23,83) 129(85,164) 54(35,83) 37(21,62) 25(16,38) 20(13,30) < 0.001
 CD8+ TCM (cells/μl) 5(3,8) 5(3,7) 5(3,8) 6(3,9) 6(3,10) 5(3,9) 0.363
 CD8 +TEM (cells/μl) 41(28,61) 41(32,53) 39(27,62) 41(26,63) 46(28,71) 39(29,64) 0.28
 CD8+TEMRA (cells/μl) 111(63,181) 119(77,193) 103(58,185) 103(54,164) 121(83,189) 115(63,194) 0.281
  1. Percentages and absolute numbers (cells/μl) of naïve (TNAIVE), central memory (TCM), effector memory (TEM), terminally differentiated (TEMRA)
  2. *p for trend across age groups < 0.05