From: Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy
 | DN (n = 30) | PGN-DM (n = 30) | ||||||
---|---|---|---|---|---|---|---|---|
 | MPC1 | MPC2 | MPC1 | MPC2 | ||||
 | r | p | r | p | r | p | r | p |
Gender | −0.106 | 0.578 | −0.01 | 0.96 | 0.124 | 0.514 | 0.164 | 0.387 |
Age (years) | − 0.209 | 0.267 | 0.155 | 0.415 | 0.279 | 0.136 | 0.485 | 0.007 |
Diabetes duration (years) | 0.085 | 0.655 | 0.123 | 0.517 | − 0.088 | 0.646 | 0.1 | 0.601 |
Hypertension | −0.067 | 0.723 | 0.116 | 0.543 | 0.247 | 0.188 | 0.116 | 0.542 |
SBP (mmHg) | −0.111 | 0.559 | 0.052 | 0.784 | 0.159 | 0.401 | 0.264 | 0.158 |
DBP (mmHg) | −0.1 | 0.597 | −0.053 | 0.781 | −0.079 | 0.677 | −0.124 | 0.515 |
Hb (g/L) | 0.402 | 0.028 | 0.347 | 0.061 | 0.11 | 0.564 | −0.143 | 0.452 |
HbA1C (%) | 0.375 | 0.065 | 0.437 | 0.029 | 0.16 | 0.436 | 0.089 | 0.664 |
Fasting glucose (mmol/L) | 0.167 | 0.379 | 0.214 | 0.257 | 0.194 | 0.304 | 0.113 | 0.553 |
Total cholesterol (mg/dL) | −0.014 | 0.94 | 0.102 | 0.593 | 0.094 | 0.623 | 0.196 | 0.299 |
LDL cholesterol (mg/dL) | −0.058 | 0.762 | 0.104 | 0.585 | 0.09 | 0.635 | 0.136 | 0.475 |
HDL cholesterol (mg/dL) | 0.09 | 0.636 | 0.002 | 0.992 | 0.323 | 0.082 | 0.374 | 0.042 |
Triglyceride (mg/dL) | 0.031 | 0.871 | 0.153 | 0.421 | −0.208 | 0.269 | −0.306 | 0.1 |
Albumin (g/L) | 0.081 | 0.669 | 0.035 | 0.854 | 0.256 | 0.173 | 0.21 | 0.265 |
Serum creatinine (umol/L) | −0.411 | 0.024 | −0.387 | 0.034 | −0.182 | 0.335 | −0.162 | 0.391 |
eGFR (ml/min/1.73 m2) | 0.474 | 0.008 | 0.383 | 0.037 | 0.14 | 0.461 | −0.017 | 0.928 |
Serum cystatin C (mg/L) | −0.379 | 0.099 | −0.4 | 0.081 | −0.198 | 0.517 | −0.082 | 0.789 |
BUN (mmol/L) | −0.619 | < 0.001 | −0.578 | 0.001 | −0.003 | 0.989 | 0.046 | 0.809 |
Uric acid (umol/L) | −0.066 | 0.73 | −0.288 | 0.123 | −0.044 | 0.816 | −0.202 | 0.284 |
Serum NGAL (ng/mL) | −0.33 | 0.107 | −0.036 | 0.865 | −0.343 | 0.128 | −0.21 | 0.36 |
Urine NGAL (ng/mL) | −0.404 | 0.069 | −0.113 | 0.626 | −0.017 | 0.966 | 0.1 | 0.798 |
Urine albumin(g/24 h) | −0.282 | 0.131 | −0.145 | 0.444 | −0.447 | 0.013 | −0.36 | 0.051 |
Urine ACR (mg/g) | −0.262 | 0.187 | −0.343 | 0.08 | −0.17 | 0.578 | −0.165 | 0.59 |
Urine pH | −0.054 | 0.789 | −0.211 | 0.29 | −0.032 | 0.874 | −0.206 | 0.302 |
Urine bicarbonate (mmol/L) | −0.151 | 0.452 | −0.225 | 0.259 | 0.057 | 0.779 | −0.09 | 0.656 |
Urine titratable acid (mmol/L) | 0.052 | 0.797 | 0.223 | 0.264 | 0.249 | 0.21 | 0.205 | 0.306 |
Urine ammonia (mmol/L) | −0.06 | 0.765 | −0.006 | 0.975 | 0.184 | 0.357 | 0.173 | 0.387 |