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Table 2 Associations between MPC and clinical features in DN and PGN-DM

From: Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy

  DN (n = 30) PGN-DM (n = 30)
  MPC1 MPC2 MPC1 MPC2
  r p r p r p r p
Gender −0.106 0.578 −0.01 0.96 0.124 0.514 0.164 0.387
Age (years) − 0.209 0.267 0.155 0.415 0.279 0.136 0.485 0.007
Diabetes duration (years) 0.085 0.655 0.123 0.517 − 0.088 0.646 0.1 0.601
Hypertension −0.067 0.723 0.116 0.543 0.247 0.188 0.116 0.542
SBP (mmHg) −0.111 0.559 0.052 0.784 0.159 0.401 0.264 0.158
DBP (mmHg) −0.1 0.597 −0.053 0.781 −0.079 0.677 −0.124 0.515
Hb (g/L) 0.402 0.028 0.347 0.061 0.11 0.564 −0.143 0.452
HbA1C (%) 0.375 0.065 0.437 0.029 0.16 0.436 0.089 0.664
Fasting glucose (mmol/L) 0.167 0.379 0.214 0.257 0.194 0.304 0.113 0.553
Total cholesterol (mg/dL) −0.014 0.94 0.102 0.593 0.094 0.623 0.196 0.299
LDL cholesterol (mg/dL) −0.058 0.762 0.104 0.585 0.09 0.635 0.136 0.475
HDL cholesterol (mg/dL) 0.09 0.636 0.002 0.992 0.323 0.082 0.374 0.042
Triglyceride (mg/dL) 0.031 0.871 0.153 0.421 −0.208 0.269 −0.306 0.1
Albumin (g/L) 0.081 0.669 0.035 0.854 0.256 0.173 0.21 0.265
Serum creatinine (umol/L) −0.411 0.024 −0.387 0.034 −0.182 0.335 −0.162 0.391
eGFR (ml/min/1.73 m2) 0.474 0.008 0.383 0.037 0.14 0.461 −0.017 0.928
Serum cystatin C (mg/L) −0.379 0.099 −0.4 0.081 −0.198 0.517 −0.082 0.789
BUN (mmol/L) −0.619 < 0.001 −0.578 0.001 −0.003 0.989 0.046 0.809
Uric acid (umol/L) −0.066 0.73 −0.288 0.123 −0.044 0.816 −0.202 0.284
Serum NGAL (ng/mL) −0.33 0.107 −0.036 0.865 −0.343 0.128 −0.21 0.36
Urine NGAL (ng/mL) −0.404 0.069 −0.113 0.626 −0.017 0.966 0.1 0.798
Urine albumin(g/24 h) −0.282 0.131 −0.145 0.444 −0.447 0.013 −0.36 0.051
Urine ACR (mg/g) −0.262 0.187 −0.343 0.08 −0.17 0.578 −0.165 0.59
Urine pH −0.054 0.789 −0.211 0.29 −0.032 0.874 −0.206 0.302
Urine bicarbonate (mmol/L) −0.151 0.452 −0.225 0.259 0.057 0.779 −0.09 0.656
Urine titratable acid (mmol/L) 0.052 0.797 0.223 0.264 0.249 0.21 0.205 0.306
Urine ammonia (mmol/L) −0.06 0.765 −0.006 0.975 0.184 0.357 0.173 0.387