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Table 2 Associations between MPC and clinical features in DN and PGN-DM

From: Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy

 

DN (n = 30)

PGN-DM (n = 30)

 

MPC1

MPC2

MPC1

MPC2

 

r

p

r

p

r

p

r

p

Gender

−0.106

0.578

−0.01

0.96

0.124

0.514

0.164

0.387

Age (years)

− 0.209

0.267

0.155

0.415

0.279

0.136

0.485

0.007

Diabetes duration (years)

0.085

0.655

0.123

0.517

− 0.088

0.646

0.1

0.601

Hypertension

−0.067

0.723

0.116

0.543

0.247

0.188

0.116

0.542

SBP (mmHg)

−0.111

0.559

0.052

0.784

0.159

0.401

0.264

0.158

DBP (mmHg)

−0.1

0.597

−0.053

0.781

−0.079

0.677

−0.124

0.515

Hb (g/L)

0.402

0.028

0.347

0.061

0.11

0.564

−0.143

0.452

HbA1C (%)

0.375

0.065

0.437

0.029

0.16

0.436

0.089

0.664

Fasting glucose (mmol/L)

0.167

0.379

0.214

0.257

0.194

0.304

0.113

0.553

Total cholesterol (mg/dL)

−0.014

0.94

0.102

0.593

0.094

0.623

0.196

0.299

LDL cholesterol (mg/dL)

−0.058

0.762

0.104

0.585

0.09

0.635

0.136

0.475

HDL cholesterol (mg/dL)

0.09

0.636

0.002

0.992

0.323

0.082

0.374

0.042

Triglyceride (mg/dL)

0.031

0.871

0.153

0.421

−0.208

0.269

−0.306

0.1

Albumin (g/L)

0.081

0.669

0.035

0.854

0.256

0.173

0.21

0.265

Serum creatinine (umol/L)

−0.411

0.024

−0.387

0.034

−0.182

0.335

−0.162

0.391

eGFR (ml/min/1.73 m2)

0.474

0.008

0.383

0.037

0.14

0.461

−0.017

0.928

Serum cystatin C (mg/L)

−0.379

0.099

−0.4

0.081

−0.198

0.517

−0.082

0.789

BUN (mmol/L)

−0.619

< 0.001

−0.578

0.001

−0.003

0.989

0.046

0.809

Uric acid (umol/L)

−0.066

0.73

−0.288

0.123

−0.044

0.816

−0.202

0.284

Serum NGAL (ng/mL)

−0.33

0.107

−0.036

0.865

−0.343

0.128

−0.21

0.36

Urine NGAL (ng/mL)

−0.404

0.069

−0.113

0.626

−0.017

0.966

0.1

0.798

Urine albumin(g/24 h)

−0.282

0.131

−0.145

0.444

−0.447

0.013

−0.36

0.051

Urine ACR (mg/g)

−0.262

0.187

−0.343

0.08

−0.17

0.578

−0.165

0.59

Urine pH

−0.054

0.789

−0.211

0.29

−0.032

0.874

−0.206

0.302

Urine bicarbonate (mmol/L)

−0.151

0.452

−0.225

0.259

0.057

0.779

−0.09

0.656

Urine titratable acid (mmol/L)

0.052

0.797

0.223

0.264

0.249

0.21

0.205

0.306

Urine ammonia (mmol/L)

−0.06

0.765

−0.006

0.975

0.184

0.357

0.173

0.387