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Table 1 The titers of anti-C.E.R.A. and anti-epoetin-beta antibodies

From: Antibody-mediated pure red cell aplasia related with epoetin-beta pegol (C.E.R.A.) as an erythropoietic agent: case report of a dialysis patient

  Anti-C.E.R.A. antibody Anti-epoetin-beta antibody
1st assay 2st assay 1st assay 2st assay
Titer Normal range Value (%) Normal range Titer Normal range Value (%) Normal range
At diagnosis 0.0275 0.0123 79.6 55.6 1.1202 0.3973 94.4 15.6
On the 20th week after the therapy 0.0075 0.0125    0.125 0.1858   
On the 32th week after the therapy 0.015 0.0235    0.1045 0.196   
On the 20th week after the re-administration 0.0165 0.0283    0.104 0.1633   
  1. 1st assay represents the titer of anti-C.E.R.A. or anti-epoetin-beta antibody determined using an enzyme-linked immunosorbent assay
  2. 2st assay shows the decline rate in the titer of anti-C.E.R.A. or anti-epoetin-beta antibody when excess recombinant C.E.R.A. or epoetin-beta proteins was added