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Table 3 ANG-2 Renal Clearance in Subjects with and without AKI

From: Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes

Timed Urine Collection

Average Serum Creatinine (mg/dL)

Average Plasma ANG-2 (pg/mL)

Urine ANG2 (pg/mL)

ANG-2 Renal Clearance (mL/min)

1

3.24

29,312.89

4671.87

0.216

2

3.52

27,136.51

5915.63

0.353

3

0.82

5061.54

10.00

0.002

4

0.89

4782.57

553.81

0.161

5

0.61

4435.69

169.09

0.064

6

0.53

3867.01

10.00

0.006

7

0.75

10,426.38

11.80

0.004

8

0.69

9699.06

14.58

0.002

9

0.60

6593.72

10.00

0.004

10

0.82

8350.90

190.68

0.010

11

0.71

15,886.06

220.09

0.003

12

0.69

10,096.66

243.74

0.018

13

2.57

26,288.02

2097.31

0.079

14

2.24

24,769.31

1967.59

0.165

15

2.16

22,259.65

1696.53

0.074

16

0.99

10,839.17

10.00

0.002

17

0.44

2624.28

10.00

0.007

18

1.20

18,067.95

192.79

0.014

19

1.14

13,683.26

527.93

0.069

20

1.13

8829.19

245.35

0.095

  1. Serum creatinine and plasma ANG-2 calculated based on the average measurement from the plasma sample collected at the beginning and at the end of the time urine collection. Clearance calculated using the formula Clearance (X) = U(X) * V/ P(X), where U(X) represents the urine concentration of solute X, V indicates the urine volume over the 2–4-h collection period, and P (X) represents the average plasma concentrations of solute X from the initial and final blood collection