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Table 3 Hazard ratios for TBS to predict adverse outcomes related to CKD-MBD in hemodialysis patients

From: Trabecular bone score may indicate chronic kidney disease-mineral and bone disorder (CKD-MBD) phenotypes in hemodialysis patients: a prospective observational study

Adjustment

Mortality

Incident fracture

New onset CVE

HRa (95% CI)

p-value

HRa (95% CI)

p-value

HRa (95% CI)

p-value

Unadjusted

0.314 (0.098–1.004)

0.051

0.220 (0.085–0.566)

0.002

0.450 (0.188–1.075)

0.072

Age

0.640 (0.150–2.725)

0.546

0.209 (0.062–0.700)

0.011

0.573 (0.186–1.770)

0.333

Model 1

0.630 (0.141–2.826)

0.546

0.165 (0.055–0.500)

0.001

0.647 (0.208–2.014)

0.452

Model 2

0.506 (0.116–2.198)

0.363

0.084 (0.014–0.519)

0.008

0.389 (0.107–1.418)

0.153

Model 3

0.369 (0.054–2.492)

0.306

0.041 (0.003–0.488)

0.012

0.403 (0.114–1.430)

0.160

Model 4

0.362 (0.044–2.956)

0.343

0.064 (0.006–0.682)

0.023

0.334 (0.077–1.442)

0.142

  1. Model 1: adjusted for age, dialysis vintage, BMI
  2. Model 2: adjusted for model 1 plus DM, CVE
  3. Model 3: adjusted for model 2 plus PTH
  4. Model 4: adjusted for model 3 plus hand grip test
  5. Abbreviations: CI Confidence interval, CKD-MBD Chronic kidney disease-mineral and bone disorder, HR Hazard ratio, CVE Cardiovascular events, TBS Trabecular bone score
  6. aHazard ratios per 0.1 higher TBS