Risk factors for renal failure and short-term prognosis in patients with spontaneous intracerebral haemorrhage complicated by acute kidney injury

Table 2 Univariate analysis of risk factors for deterioration to AKI stage 3 in SICH patients complicated with AKI

Characteristics	OR	95%CI	P value
Demographics
Age ≥ 65 years	1.081	0.714–1.637	0.712
Male	1.206	0.790–1.840	0.385
Medical history
Diabetes	1.546	0.951–2.512	0.079
Hypertension	1.135	0.762–1.691	0.532
ICU admission	1.589	1.034–2.470	0.035
Mechanical ventilation	2.540	1.649–3.911	<0.001
Medication used
Mannitol	1.025	0.661–1.591	0.912
NSAID	1.057	0.701–1.591	0.791
Colloids	2.186	1.377–3.472	0.001
Vasoactive drugs	1.703	1.109–2.611	0.015
Diuretics	3.694	2.136–6.389	<0.001
Aminoglycosides	1.228	0.694–2.171	0.48
Laboratory data
Serum sodium (normal)	0.214		<0.001
Hypernatronemia*	1.719	1.101–2.685	0.017
Hypernatronemia†	2.42	1.186–4.936	0.015
Hypernatronemia‡	8.061	3.615–17.971	<0.001
Hyperchloremia	1.994	1.340–2.996	0.001
Metabolic acidosis	2.186	1.447–3.301	<0.001
Hypoproteinemia	1.028	0.689–1.534	0.893
Elevated serum creatine kinase	2.962	1.981–4.428	<0.001
Hyperuricemia	3.074	1.990–4.748	<0.001
Elevated white blood cell count	1.716	1.107–2.662	0.016
Anemia	1.637	1.081–2.478	0.02
Proteinuria	1.82	1.505–2.200	<0.001
Hematuresis	1.406	1.219–1.662	<0.001

ICU admission intensive care unit admission;Serum sodium (normal): serum sodium concentration ≤ 145 mmol/L; Hypernatronemia*: serum sodium concentration > 145 mmol/L & ≤ 160 mmol/L; Hypernatronemia†: serum sodium concentration > 160 mmol/L & ≤ 170 mmol/L; Hypernatronemia‡: serum sodium concentration > 170 mmol/L.

ISSN: 1471-2369