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Table 1 Baseline characteristics of the study population stratified by levels of eGFR

From: Efficacy of different urinary uric acid indicators in patients with chronic kidney disease

Variables Overall
(n = 625)
CKD1
(n = 130)
CKD2
(n = 164)
CKD3
(n = 147)
CKD4
(n = 86)
CKD5
(n = 97)
P value
Male gender (%) 50.9 50.8 56.7 45.6 48.8 50.5 0.4021
Age (years) 57.9 ± 16.4 46.2 ± 14.9 56.4 ± 14.7 62.4 ± 15.4 63.8 ± 15.4 63.9 ± 14.8 < 0.001
BMI (kg/m2) 24.3 ± 3.9 23.7 ± 3.8 24.7 ± 4.4 24.7 ± 3.5 24.2 ± 3.7 24.1 ± 4.0 0.204
Hypertension (%) 66.8 32.1 61.3 76.2 83.6 83.8 < 0.0001
Diabetes (%) 32 19.2 29 38.1 29.5 43.8 0.0118
HB (g/L) 115.9 ± 24.4 128.6 ± 18.3 131.1 ± 19.2 122.3 ± 17.7 102.7 ± 17.9 90.3 ± 18.7 < 0.001
CRP (mg/L) 3.7 (1.1–8.2) 2.8 (0.8–6.2) 3.2 (1.0–6.5) 3.8 (1.1–9.5) 4.7 (1.2–9.0) 6.0 (1.8–12.2) < 0.001
HbA1C (%) 6.0 ± 1.1 6.0 ± 1.5 6.0 ± 0.9 6.2 ± 1.1 6.1 ± 1.0 5.9 ± 1.0 0.637
ALB (g/L) 37.8 ± 7.6 38.2 ± 7.6 38.8 ± 9.7 38.6 ± 6.4 36.7 ± 6.6 35.5 ± 5.5 0.004
LDL (mmol/L) 2.8 ± 1.1 3.1 ± 1.2 3.0 ± 1.3 2.7 ± 0.9 2.7 ± 1.0 2.4 ± 0.8 < 0.001
HDL (mmol/L) 1.3 ± 0.4 1.4 ± 0.3 1.3 ± 0.4 1.3 ± 0.4 1.3 ± 0.3 1.2 ± 0.3 0.003
TC (mmol/L) 4.9 ± 1.5 5.1 ± 1.7 5.1 ± 1.7 4.7 ± 1.4 4.9 ± 1.5 4.4 ± 1.1 0.002
TG (mmol/L) 1.9 ± 1.4 1.9 ± 1.3 2.0 ± 1.8 1.9 ± 1.1 2.1 ± 1.7 1.6 ± 0.8 0.188
BUN (mmol/L) 10.5 ± 8.2 4.9 ± 1.3 6.6 ± 5.1 8.5 ± 2.7 13.2 ± 4.6 24.9 ± 8.4 < 0.001
Scr (μmol/L) 199.0 ± 218.6 63.5 ± 11.5 89.8 ± 15.6 134.9 ± 28.5 227.5 ± 43.7 631.6 ± 250.3 < 0.001
SUA (μmol/L) 393.8 ± 110.7 329.1 ± 89.3 367.1 ± 102.2 423.6 ± 96.5 414.8 ± 106.6 461.0 ± 116.7 < 0.001
UUA (mmol/24 h) 2.3 (1.7–3.1) 2.9 (2.3–3.6) 2.7 (2.2–3.4) 2.3 (1.7–2.8) 1.8 (1.3–2.4) 1.4 (0.8–1.9) < 0.001
Ccr (mL/min) 60.1 (26.7–93.1) 114.3 (92.9–135.6) 83.2 (69.3–101.7) 52.0 (43.0–65.2) 26.4 (20.8–35.1) 9.3 (5.9–14.3) < 0.001
Cur (mL/min) 4.3 (2.7–6.0) 6.6 (4.6–8.6) 5.2 (4.2–6.9) 3.8 (3.0–4.9) 2.9 (2.2–4.4) 2.0 (1.3–2.7) < 0.001
FLur (μmol/min) 22.3 (10.9–33.1) 38.2 (26.9–47.6) 30.7 (22.4–41.8) 22.2 (16.2–26.8) 11.2 (7.6–15.9) 4.1 (2.7–6.3) < 0.001
EurGF (μmol/L) 26.7 (20.2–46.1) 18.0 (15.2–20.7) 22.4 (19.8–27.1) 29.2 (23.6–37.6) 50.6 (35.7–58.6) 91.2 (67.0–135.4) < 0.001
FEur (%) 7.3 (5.5–11.3) 5.5 (4.3–7.1) 6.1 (5.1–7.6) 7.3 (5.8–9.2) 11.1 (7.9–15.3) 20.7 (15.6–29.7) < 0.001