Table 2 Adjusted effects of renal function on levels of uric acid
From: Efficacy of different urinary uric acid indicators in patients with chronic kidney disease
All(n = 625) | SUA (μmol/L)β | UUA (mmol/24 h)β | Cur (mL/min)β | FLur (μmol/min)β | FEur (%)β |
|---|---|---|---|---|---|
(95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | |
Continuous eGFR (mL/min/1.732) | −1.41 (− 1.64, − 1.17)** | 0.01 (0.01, 0.02)** | 0.04 (0.04, 0.05)** | 0.33 (0.29, 0.36)** | −0.15 (− 0.16, − 0.13)** |
Clinical cutoffs | |||||
CKD 1 (n = 130) | Reference | Reference | Reference | Reference | Reference |
CKD 2 (n = 164) | 35.36 (12.13,58.59) | −0.17(−0.50, 0.17) | −1.02 (− 1.78, − 0.27) | −6.13(−9.68, −2.59)** | 1.23(− 0.51, 2.96) |
CKD 3 (n=147) | 99.55 (74.95,124.16)** | −0.43(− 0.78, − 0.07)* | −2.49 (− 3.29, − 1.70)** | − 15.93(− 19.68, − 12.17)** | 2.80 (0.95, 4.65)** |
CKD 4 (n = 86) | 99.08 (71.00,127.17)** | −0.87 (− 1.27, 0.46)** | −3.32 (− 4.24, − 2.41)** | − 24.80(− 29.09, − 20.52)** | 6.58 (4.47, 8.69)** |
CKD 5 (n = 97) | 146.02 (118.80,173.25)** | −1.41(− 1.80, 1.01)** | −4.59 (− 5.47, − 3.70) ** | − 32.01(− 36.17, − 27.85)** | 17.41 (15.37, 19.46)** |