Table 1 Characteristics of CKD patients according to DM comorbidity and GFR category
Parameters | Total (n = 256) | DM-CKD (n = 107) | Non-DM-CKD (n = 149) | P value3,4 | ||||
|---|---|---|---|---|---|---|---|---|
Early-CKD (n = 49) | Late-CKD (n = 58) | Early-CKD (n = 77) | Late-CKD (n = 72) | DM comorbidity | GFR category | Interaction | ||
Sociodemographic parameter | ||||||||
 Age (years) | 59.9 ± 12.11 | 60.7 ± 11.3a | 63.4 ± 11.0a | 56.0 ± 12.0b | 60.5 ± 12.7a | < 0.01 | < 0.01 | 1.00 |
Medication and supplements | ||||||||
 Antihypertensive drug use, n (%) | 223 (87.1) | 44 (89.8) | 53 (91.4) | 70 (90.9) | 56 (77.8) |  | < 0.05 |  |
Clinical parameters | ||||||||
 eGFR (mL/min/1.73m2) | 50.4 ± 27.31 | 71.4 ± 20.0a | 29.0 ± 8.9b | 74.6 ± 19.6a | 27.5 ± 10.0b | 0.08 | < 0.001 | 1.00 |
 SBP (mmHg)5 | 128.1 ± 12.7 | 129.3 ± 9.5ab | 132.4 ± 15.5a | 124.9 ± 12.0b | 127.1 ± 11.8ab | < 0.01 | 0.07 | 1.00 |
 DBP (mmHg)5 | 77.8 ± 9.9 | 78.2 ± 9.9 | 76.7 ± 10.2 | 78.0 ± 10.6 | 78.1 ± 9.4 | 0.63 | 0.52 | 0.66 |
 Malnutrition, n (%)6 | 31 (12.1)2 | 6 (12.2) | 12 (20.7) | 1 (1.3) | 12 (16.7) |  | < 0.01 |  |
Biochemical data | ||||||||
 Creatinine (mg/dL) | ||||||||
  Male | 1.83 ± 0.88 | 1.2 ± 0.3b | 2.3 ± 0.7a | 1.3 ± 0.2b | 2.6 ± 1.0a | 0.70 | < 0.001 | 0.15 |
  Female | 1.64 ± 1.02 | 0.8 ± 0.2b | 2.4 ± 1.0a | 0.8 ± 0.2b | 2.4 ± 1.0a | 0.96 | < 0.001 | 0.53 |
  BUN (mg/dL) | 26.9 ± 15.3 | 18.5 ± 6.8b | 35.0 ± 17.3a | 16.3 ± 4.3b | 37.2 ± 14.8a | 0.24 | < 0.001 | 0.08 |
  Glucose (mg/dL) | 114.5 ± 30.7 | 127.3 ± 28.7a | 138.0 ± 45.6a | 101.6 ± 10.4b | 100.6 ± 9.7b | < 0.001 | 0.09 | 0.21 |
  Serum albumin (g/dL) | 4.2 ± 0.6 | 4.3 ± 0.3a | 4.1 ± 0.4c | 4.2 ± 0.3ab | 4.2 ± 0.3b | 0.69 | < 0.001 | < 0.01 |