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Table 3 Intraoperative parameters

From: Mannitol and renal graft injury in patients undergoing deceased donor renal transplantation – a randomized controlled clinical trial

 

Mannitol

(n = 16)

Placebo

(n = 16)

p- Value

Duration

 Anesthesia, hrs

3.6

[3.1, 4.1]

3.8

[3.4, 4.3]

0.35

 Surgery, hrs

2.6

[2.2, 3.2]

2.9

[2.4, 3.5]

0.55

 Arterial Clamp, min

16

[10, 23]

24

[12, 29]

0.25

 Venous Clamp, min

22

[16, 25]

20

[15, 25]

0.47

Fluid & Hemodynamics

 Total Fluid, mL

1.870

±817

1.823

±558

0.85

 Blood Loss, mL

200

[100, 588]

175

[0, 375]

0.49

 MAP, TWA mmHg

77

[74, 91]

79

[74, 82]

0.74

 SV, mL

51

[43, 82]

64

[52, 72]

0.74

 CO, L min−1

3.1

[2.5, 5.0]

4.3

[2.9, 4.7]

0.97

 CVP, mmHg

13

±4

12

±4

0.47

Anesthesia Variables

 Propofol, mg

190

[123, 200]

200

[90, 230]

0.92

 Fentanyl, μg

650

[500, 750]

550

[400, 800]

0.92

 et Sevoflurane TWA, %

1.3

±0.5

1.5

±0.3

0.36

 SpO2, %

99

[98, 99]

98

[96, 99]

0.15

 Core, T°C

36.3

±0.4

36.4

±0.5

0.32

Phenylephrine

 No. of Patients, (%)

8

(50)

11

(69)

0.78

 Cumulative Dose, mg

0.02

[0.0, 0.4]

0.08

[0.0, 0.19]

0.99

Noradrenaline

 No. of Patients, (%)

5

(32)

5

(32)

1.00

 Cumulative Dose, mg

0.14

[0.00, 0.29]

0.11

[0.00, 0.20]

0.86

Central Venous Blood Gas Analysis

 pH

7.36

±0.1

7.37

±0.1

0.40

 pCO2,mmHg

44

±7

46

±7

0.34

 pO2,mmHg

49

[42; 56]

52

[46; 56]

0.38

 Hb, g/dL

9.7

±1.4

9.6

±1.3

0.62

 Na+, mmol/L

136

±3

138

±2

0.04

 K+, mmol/L

4.7

±0.7

4.7

±0.4

0.93

 Lactate, mmol/L

0.8

±0.2

0.8

±0.3

0.49

  1. Summary characteristics of intraoperative measurements presented as means ±SD or medians [25th percentile, 75th percentile]. All P-values are for unpaired Student’s t-tests or Mann-Whitney-U tests as appropriate. MAP mean arterial pressure; TWA time weighted average; SV stroke volume; FTc corrected flow time; CO cardiac output, CVP central venous pressure, pCO2 partial pressure of carbon dioxide; pO2 partial pressure of oxygen; BE base excess; Hb hemoglobin