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Table 6 Factors associated with chronic kidney disease by univariate and multivariate analysis (N = 890)

From: Prevalence of chronic kidney disease and its associated factors in Malaysia; findings from a nationwide population-based cross-sectional study

Variable

N

% with CKD

p-value

Unadjusted OR

(95% CI)

p-value

Adjusted ORa

(95% CI)

Age (years)

  

< 0.001

1.08 (1.06,1.09)

< 0.001

1.06 (1.04,1.08)

Gender

 Male

59

16.1

 

1

 

1

 Female

99

18.9

0.287

1.21 (0.85,1.73)

0.198

1.50 (0.81, 2.79)

Race

 Malay

110

18.6

 

1

 

1

 Chinese

11

12.6

0.176

0.63 (0.33, 1.23)

0.196

0.60 (0.27, 1.31)

 Indian

7

13.0

0.303

0.65 (0.29,1.48)

0.204

0.53 (0.20, 1.42)

 Others

30

18.9

0.949

1.02 (0.65, 1.59)

0.153

1.53 (0.86, 2.73)

Strata

 Urban

56

15.1

 

1

 

1

 Rural

102

19.6

0.085

1.37 (0.96,1.96)

0.141

1.42 (0.89,2.27)

Household Income

 Low (<RM 2614 per month)

112

19.4

 

1

 

1

 Middle (RM 2614–10,455

per month)

42

14.8

0.506

1.44 (0.49,4.24)

0.133

1.48 (0.89, 2.45)

 High (≥RM 10456 per month)

4

14.3

0.943

1.04 (0.34,3.15)

0.307

1.93 (0.55, 6.87)

Ever Cigarette Smoking

 Yes

47

16.6

0.542

0.89 (0.61,1.30)

0.251

1.46 (0.77, 2.78)

 No

111

18.3

 

1

 

1

Physical Activity

 Active

83

15.6

 

1

 

1

 Inactive

75

21.0

0.038

1.442 (1.02,2.04)

0.368

1.23 (0.79, 1.91)

Diabetes

 Yes

80

46.0

< 0.001

6.96 (4.76,10.18)

< 0.001

3.32 (2.20,5.03)

 No

78

10.9

 

1

 

1

Hypertension

 Yes

141

31.1

< 0.001

11.14 (6.60,18.81)

< 0.001

3.72 (2.08,6.66)

 No

17

3.9

 

1

 

1

Hypercholesterolemia

 Yes

79

30.9

< 0.001

3.08 (2.13,4.45)

0.513

1.17 (0.73, 1.87)

 No

67

12.7

 

1

 

1

Heart Disease

 Yes

18

30.0

0.017

2.03 (1.14,3.64)

0.152

0.58 (0.27, 1.22)

 No

136

17.4

 

1

 

1

Family History of Kidney Disease

 Yes

17

20.5

0.521

1.20 (0.68,2.11)

0.099

1.89 (0.89, 4.01)

 No

139

17.6

 

1

 

1

Painkiller Use

 Yes

80

16.4

0.221

0.81 (0.57,1.14)

0.723

1.08 (0.70, 1.68)

 No

78

19.6

 

1

 

1

Traditional Medicine Use

 Yes

17

15.3

0.468

0.82 (0.47,1.41)

0.281

0.69 (0.35,1.36)

 No

140

18.1

 

1

 

1

BMI (kg/m2)

  

< 0.001

1.07 (1.03,1.10)

0.006

1.06 (1.02,1.10)

Abdominal obesity

 Yes

123

20.9

0.001

2.02 (1.35,3.02)

0.260

0.68 (0.35, 1.33)

 No

35

11.6

1

  

1

  1. Definition of chronic kidney disease status: eGFR< 60 ml/min/1.73 m2 and/or albuminuria
  2. OR Odds Ratio, CI Confidence Interval, eGFR estimated glomerular filtration rate, BMI Body Mass Index
  3. aFinal model was adjusted by age, diabetes, hypertension, and BMI