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Table 1 Baseline characteristics of study participants

From: New oral spherical carbon adsorbent effectively reduces serum indoxyl sulfate levels in moderate to advanced chronic kidney disease patients: a multicenter, prospective, open-label study

 

(n = 87)

Age (years)

62.8 ± 13.7

Sex, male (%)

70 (80.5)

BMI (kg/m2)

25.9 ± 4.1

Systolic BP (mmHg)

131.2 ± 11.7

Diastolic BP (mmHg)

79.0 ± 11.2

CKD duration (months)

70.0 ± 47.2

CKD stage

 Stage 3 (%)

45 (51.7)

 Stage 4 (%)

38 (43.7)

 Stage 5 (%)

3 (3.4)

Comorbidities (%)

 Hypertension

67 (77.0)

 Diabetes

41 (48.3)

 Cardiovascular disease

13 (14.9)

 Cerebrovascular disease

10 (11.5)

Laboratory data

 Indoxyl sulfate (mg/dL)

0.46 ± 0.41

 BUN (mg/dL)

35.1 ± 12.7

 Serum creatinine (mg/dL)

2.5 ± 0.8

 eGFR (mL/min/1.73m2)

31.6 ± 11.3

 Urine PCR (mg/g)

3613.4 ± 4203.2

 Hemoglobin (g/dL)

12.1 ± 2.0

 Phosphorus (mg/dL)

3.6 ± 0.6

 Intact PTH (mg/dL)

104.0 ± 101.3

 Uric acid (mg/dL)

7.1 ± 1.8

 Albumin (g/dL)

3.9 ± 0.6

 Serum Na (mmol/L)

139.5 ± 2.5

 Serum K (mmol/L)

4.8 ± 0.6

 Total CO2 (mmol/L)

23.8 ± 3.3

  1. Data are presented as mean ± standard deviation or number (percentage) of subjects
  2. Abbreviation: BMI body mass index, BP blood pressure, CKD chronic kidney disease, eGFR estimated glomerular filtration rate, PCR protein to creatinine ratio, PTH parathyroid hormone