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Table 1 Baseline characteristics of the study cohort according to plasma fibrinogen quartiles

From: Plasma fibrinogen and mortality in patients undergoing peritoneal dialysis: a prospective cohort study

Variables

Total (n = 1603)

Plasma fibrinogen quartiles

P

Q1 (<  3.19) (n = 400)

Q2 (3.19–3.80) (n = 405)

Q3 (3.80–4.72) (n = 398)

Q4 (>  4.72) (n = 400)

Plasma fibrinogen (g/L)

4.12 ± 1.38

2.72 ± 0.35

3.48 ± 0.18

4.26 ± 0.27

6.04 ± 1.16

<  0.001

Age (y)

47.4 ± 15.3

43.9 ± 14.9

45.9 ± 15.6

47.8 ± 14.5

52.1 ± 14.8

<  0.001

Male, n (%)

955 (59.6)

220 (55.0)

234 (57.8)

245 (61.6)

256 (64.0)

0.05

Smokers, n (%)

331 (20.6)

65 (16.3)

76 (18.8)

81 (20.4)

109 (27.3)

0.001

History of CV events, n (%)

319 (19.9)

47 (11.8)

61 (15.1)

89 (22.4)

122 (30.5)

<  0.001

Diabetes, n (%)

410 (25.6)

49 (12.3)

79 (19.5)

114 (28.6)

168 (42.0)

<  0.001

Hypertension, n (%)

1416 (88.3)

353 (88.3)

358 (88.4)

356 (89.4)

349 (87.3)

0.82

BMI (kg/m2)

22.04 ± 3.29

21.15 ± 2.78

21.66 ± 3.15

22.31 ± 3.19

23.07 ± 3.68

<  0.001

SBP (mmHg)

154.3 ± 24.8

150.4 ± 24.4

154.8 ± 23.7

157.3 ± 27.2

154.8 ± 23.5

0.002

DBP (mmHg)

88.4 ± 15.6

88.4 ± 16.3

88.6 ± 14.8

89.6 ± 16.1

86.7 ± 15.3

0.07

Hemoglobin (g/L)

79.1 ± 18.6

78.9 ± 19.1

77.9 ± 18.9

80.0 ± 18.6

79.8 ± 18.0

0.36

Blood platelet count (10 × 109/L)

19.3 ± 8.0

16.5 ± 6.6

17.7 ± 7.2

19.8 ± 7.5

23.4 ± 8.9

<  0.001

Serum potassium (mmol/L)

4.65 ± 0.84

4.69 ± 0.83

4.73 ± 0.80

4.68 ± 0.84

4.50 ± 0.86

<  0.001

Serum albumin (g/L)

34.8 ± 5.1

35.9 ± 5.1

35.1 ± 4.7

34.7 ± 5.0

33.3 ± 5.3

<  0.001

TC (mmol/L)

4.72 ± 1.43

4.44 ± 1.31

4.53 ± 1.13

4.91 ± 1.60

4.98 ± 1.57

<  0.001

TG (mmol/L)

1.30 (0.93–1.88)

1.15 (0.80–1.61)

1.26 (0.94–1.84)

1.32 (0.97–1.88)

1.49 (1.02–2.17)

<  0.001

LDL-C (mmol/L)

2.83 ± 1.09

2.59 ± 0.97

2.69 ± 0.85

3.00 ± 1.23

3.05 ± 1.19

<  0.001

HDL-C (mmol/L)

1.05 ± 0.33

1.11 ± 0.34

1.04 ± 0.32

1.05 ± 0.33

1.00 ± 0.31

<  0.001

hs-CRP (mg/L)

2.23 (0.74–8.49)

1.16 (0.44–4.08)

1.66 (0.49–6.29)

2.91 (1.01–9.50)

5.09 (1.47–11.79)

<  0.001

eGFR (mL/min/1.73 m2)

5.2 ± 2.4

5.3 ± 2.4

5.1 ± 2.2

5.2 ± 2.6

5.3 ± 2.5

0.62

Antiplatelet agents, n (%)

182 (11.4)

25 (6.3)

38 (9.4)

46 (11.6)

73 (18.3)

<  0.001

Lipid-lowering drugs, n (%)

182 (11.4)

23 (5.8)

40 (9.9)

49 (12.3)

70 (17.5)

<  0.001

  1. Note: Continuous quantitative variables are described as means ± standard deviations or medians (interquartile ranges, 1/4–3/4). Categorical data are described as frequencies (percentages)
  2. Abbreviations: Q1–Q4 lowest to highest quartile, CV cardiovascular, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglycerides, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, hs-CRP hypersensitive C-reactive protein, eGFR estimated glomerular filtration rate
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BMC Nephrology

ISSN: 1471-2369

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