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Table 3 Association of plasma fibrinogen quartiles with CV and all-cause mortality

From: Plasma fibrinogen and mortality in patients undergoing peritoneal dialysis: a prospective cohort study

Variables Q1 (n = 400) Q3 (n = 398) Q4 (n = 400)
HR (95% CI) P HR (95% CI) P HR (95% CI) P
CV mortality
 Unadjusted 0.86 (0.55–1.34) 0.49 1.74 (1.18–2.58) 0.005 2.43 (1.68–3.51) <  0.001
 Model 1a 0.92 (0.59–1.44) 0.71 1.58 (1.07–2.34) 0.02 1.93 (1.33–2.79) <  0.001
 Model 2b 1.04 (0.65–1.64) 0.89 1.42 (0.94–2.13) 0.09 1.74 (1.19–2.55) 0.004
 Model 3c 1.18 (0.72–1.94) 0.52 1.46 (0.92–2.32) 0.11 1.76 (1.13–2.72) 0.01
 Model 4d 1.18 (0.72–1.95) 0.51 1.47 (0.93–2.33) 0.10 1.78 (1.15–2.77) 0.01
All-cause mortality
 Unadjusted 0.95 (0.71–1.28) 0.74 1.54 (1.18–2.03) 0.002 2.09 (1.62–2.70) <  0.001
 Model 1a 1.00 (0.75–1.35) 0.99 1.41 (1.08–1.86) 0.01 1.67 (1.29–2.16) < 0.001
 Model 2b 1.08 (0.80–1.47) 0.60 1.26 (0.95–1.67) 0.11 1.45 (1.11–1.89) 0.006
 Model 3c 1.19 (0.85–1.67) 0.30 1.28 (0.93–1.76) 0.13 1.51 (1.11–2.06) 0.009
 Model 4d 1.20 (0.86–1.68) 0.28 1.29 (0.93–1.78) 0.13 1.53 (1.12–2.09) 0.007
  1. Note: The second quartile (Q2) was selected as the reference (n = 405). Hypersensitive C-reactive protein was log-transformed
  2. Abbreviations: Q1 to Q4 lowest to highest quartile, HR hazard ratio, CI confidence interval, CV cardiovascular
  3. a Adjusted for age and sex
  4. b Adjusted for model 1 covariates and smoking, a history of cardiovascular events, diabetes, body mass index, and systolic blood pressure
  5. c Adjusted for model 2 covariates and hemoglobin, blood platelet count, serum potassium, serum albumin, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, hypersensitive C-reactive protein, and estimated glomerular filtration rate levels
  6. d Adjusted for model 3 covariates and the use of antiplatelet agents and lipid-lowering drugs