|
Variables
|
Q1 (n = 400)
|
Q3 (n = 398)
|
Q4 (n = 400)
|
|---|
|
HR (95% CI)
|
P
|
HR (95% CI)
|
P
|
HR (95% CI)
|
P
|
|---|
|
CV mortality
|
|
Unadjusted
|
0.86 (0.55–1.34)
|
0.49
|
1.74 (1.18–2.58)
|
0.005
|
2.43 (1.68–3.51)
|
< 0.001
|
|
Model 1a
|
0.92 (0.59–1.44)
|
0.71
|
1.58 (1.07–2.34)
|
0.02
|
1.93 (1.33–2.79)
|
< 0.001
|
|
Model 2b
|
1.04 (0.65–1.64)
|
0.89
|
1.42 (0.94–2.13)
|
0.09
|
1.74 (1.19–2.55)
|
0.004
|
|
Model 3c
|
1.18 (0.72–1.94)
|
0.52
|
1.46 (0.92–2.32)
|
0.11
|
1.76 (1.13–2.72)
|
0.01
|
|
Model 4d
|
1.18 (0.72–1.95)
|
0.51
|
1.47 (0.93–2.33)
|
0.10
|
1.78 (1.15–2.77)
|
0.01
|
|
All-cause mortality
|
|
Unadjusted
|
0.95 (0.71–1.28)
|
0.74
|
1.54 (1.18–2.03)
|
0.002
|
2.09 (1.62–2.70)
|
< 0.001
|
|
Model 1a
|
1.00 (0.75–1.35)
|
0.99
|
1.41 (1.08–1.86)
|
0.01
|
1.67 (1.29–2.16)
|
< 0.001
|
|
Model 2b
|
1.08 (0.80–1.47)
|
0.60
|
1.26 (0.95–1.67)
|
0.11
|
1.45 (1.11–1.89)
|
0.006
|
|
Model 3c
|
1.19 (0.85–1.67)
|
0.30
|
1.28 (0.93–1.76)
|
0.13
|
1.51 (1.11–2.06)
|
0.009
|
|
Model 4d
|
1.20 (0.86–1.68)
|
0.28
|
1.29 (0.93–1.78)
|
0.13
|
1.53 (1.12–2.09)
|
0.007
|
- Note: The second quartile (Q2) was selected as the reference (n = 405). Hypersensitive C-reactive protein was log-transformed
- Abbreviations: Q1 to Q4 lowest to highest quartile, HR hazard ratio, CI confidence interval, CV cardiovascular
- a Adjusted for age and sex
- b Adjusted for model 1 covariates and smoking, a history of cardiovascular events, diabetes, body mass index, and systolic blood pressure
- c Adjusted for model 2 covariates and hemoglobin, blood platelet count, serum potassium, serum albumin, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, hypersensitive C-reactive protein, and estimated glomerular filtration rate levels
- d Adjusted for model 3 covariates and the use of antiplatelet agents and lipid-lowering drugs
