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Table 3 The hazard of acute myocardial infarction (AMI), ischemic stroke, amputation, and hospitalization for infection for vitamin D users compared with non-users in incident hemodialysis patients using competing risk analysis with subdistribution hazard model and cause-specific hazard regression models

From: The use of activated vitamin D and risks of hospitalization for infection and amputation in incident hemodialysis patients in Taiwan: a nationwide population-based cohort study

 

AMI

Ischemic stroke

Amputation

Infection

 

SHR (95% CI)

SHR (95% CI)

SHR (95% CI)

SHR (95% CI)

Model 1

0.82 (0.73–0.91)

0.73 (0.66–0.81)

0.57 (0.50–0.65)

0.75 (0.72–0.78)

Model 2

0.89 (0.79–0.99)

0.78 (0.70–0.87)

0.58 (0.51–0.66)

0.82 (0.78–0.85)

Model 3

1.03 (0.92–1.15)

0.91 (0.82–1.01)

0.82 (0.72–0.95)

0.90 (0.87–0.94)

Model 4

1.04 (0.93–1.16)

0.92 (0.83–1.02)

0.84 (0.74–0.96)

0.91 (0.87–0.94)

Model 5

1.04 (0.93–1.16)

0.91 (0.82–1.01)

0.84 (0.74–0.96)

0.91 (0.88–0.95)

Model 6

1.01 (0.90–1.13)

0.91 (0.82–1.01)

0.84 (0.74–0.96)

0.90 (0.87–0.94)

Model 7

1.01 (0.90–1.13)

0.90 (0.81–1.01)

0.84 (0.74–0.96)

0.91 (0.88–0.95)

 

CSHR (95% CI)

CSHR (95% CI)

CSHR (95% CI)

CSHR (95% CI)

Model 1

0.74 (0.66–0.83)

0.66 (0.60–0.73)

0.52 (0.45–0.59)

0.72 (0.69–0.75)

Model 2

0.83 (0.74–0.92)

0.73 (0.66–0.81)

0.55 (0.48–0.62)

0.80 (0.77–0.83)

Model 3

0.99 (0.89–1.12)

0.89 (0.80–0.98)

0.79 (0.70–0.90)

0.90 (0.87–0.94)

Model 4

1.01 (0.90–1.13)

0.90 (0.81–0.99)

0.81 (0.71–0.93)

0.91 (0.88–0.95)

Model 5

1.01 (0.90–1.13)

0.89 (0.80–0.99)

0.82 (0.72–0.93)

0.92 (0.88–0.95)

Model 6

0.99 (0.88–1.11)

0.90 (0.81–0.99)

0.82 (0.72–0.94)

0.91 (0.87–0.95)

Model 7

0.99 (0.89–1.12)

0.90 (0.81–0.99)

0.83 (0.73–0.94)

0.92 (0.88–0.96)

  1. Model 1: unadjusted crude SHR. Model 2: adjusted for age and sex. Model 3: model 2 plus comorbidities
  2. Model 4: model 3 plus medication use. Model 5: model 4 plus vascular access type. Model 6: model 5 plus hospital and urbanization levels
  3. Model 7: model 6 plus use of calcium-based phosphate binders
  4. SHR: subdistribution hazard ratio. CI: confidence interval. CSHR: cause-specific hazard ratio