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Table 4 Multivariate adjusted competing risk model for events of amputation and infection according to dosage of activated vitamin D based on trajectory analysis

From: The use of activated vitamin D and risks of hospitalization for infection and amputation in incident hemodialysis patients in Taiwan: a nationwide population-based cohort study

 

N (%)

Events of interest (%)

Death (%)

SHR (95% CI)

Amputation

Non-user

45,069 (86.3)

2410 (5.4)

17,019 (37.7)

Reference

Conventional dose user

6820 (13.1)

210 (3.1)

1963 (28.8)

0.83 (0.72–0.96)

High dose user

325 (0.6)

3 (0.9)

73 (22.5)

0.52 (0.17–1.63)

Overall

52,214 (100)

2623 (5.0)

19,055 (36.5)

0.84 (0.74–0.96)

Infection

Non-user

38,860 (86.1)

19,586 (50.4)

4614 (11.9)

Reference

Conventional dose user

5997 (13.3)

2406 (40.1)

628 (10.5)

0.90 (0.86–0.94)

High dose user

297 (0.7)

90 (30.3)

30 (10.1)

0.69 (0.57–0.85)

Overall

45,154 (100)

22,082 (48.9)

5272 (11.7)

0.91 (0.88–0.95)

  1. The competing risk model (Fine-Gray) was adjusted by covariates including age, sex, vascular access type, baseline comorbidities, and medications
  2. Abbreviations: SHR subdistribution hazard ratio, CI confidence intervals
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