Fig. 2
From: APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress
Human kidney cells expressed APOL1-B3 in vivo. a-c To examine the presence of APOL1 isoforms in human kidney, human autopsy kidney specimens were used for immunohistochemical analysis using APOL1-B antibody and rabbit monoclonal antibody (RPR2907). Podocytes expressed APOL1 as shown by staining with RPR2907 antibody (a), and with APOL1-B antibody recognizing APOL1-B3 (b). Control rabbit IgG did not stain podocytes (c). Wilms tumor1 (WT1) was used as a podocyte marker. All glomeruli were derived from identical kidney. Scale bar indicates 40 μm in regular and 10 μm in high magnification images. Arrow and arrowhead indicate podocytes and tubular cell respectively