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Table 2 Linear regression model for AKI-D incidence and each chronic health condition for the 18 states in the primary analysis

From: Exploring reasons for state-level variation in incidence of dialysis-requiring acute kidney injury (AKI-D) in the United States

 

Prevalence (%)

Hospitalization rate

(per 1000 patients)

 

Coef. (95% CI)

P value

Coef. (95% CI)

P value

Adjusted R2

Model 1

 Diabetes mellitus

70.5 (14.6126.3)

0.02

–

–

0.350

 Hypertension

34.6 (10.5,58.7)

0.01

–

–

0.414

 CKD

65.0 (−86.8216.8)

0.37

–

–

0.345

 ASHD

70.4 (31.8108.9)

< 0.01

–

–

0.661

 Cancer (excluding skin cancer)

−41.4 (− 204.7121.9)

0.59

–

–

0.266

 COPD

54.6 (18.1,91.1)

< 0.01

–

–

0.600

 Skin Cancer

28.1 (−58.7,11.5)

0.49

–

–

0.324

Model 2

 Diabetes mellitus

–

–

3.0 (1.8,4.1)

< 0.01

0.780

 Hypertension

–

–

4.5 (2.8,6.1)

< 0.01

0.720

 CKD

–

–

0.6 (0.0,1.1)

0.05

0.251

 ASHD

–

–

2.3 (1.0,3.6)

< 0.01

0.509

 Cancer (excluding skin cancer)

–

–

See Fig. 3a

< 0.01

0.648

 COPD

–

–

1.7 (0.3,3.1)

0.02

0.573

 Skin Cancer

–

–

4.1 (−16.4,24.6)

0.67

0.305

Model 3

 Diabetes mellitus

53.4 (42.7,64.1)

< 0.01

2.9 (2.6,3.3)

< 0.01

0.980

 Hypertension

25.6 (17.7,33.5)

< 0.01

3.9 (3.1,4.7)

< 0.01

0.940

 CKD

237.7 (143.9331.6)

< 0.01

1.0 (0.6,1.3)

< 0.01

0.823

 ASHD

61.7 (41.9,81.4)

< 0.01

1.6 (1.0,2.2)

< 0.01

0.915

 Cancer (excluding skin cancer)

23.9 (− 79.8127.6)

0.62

See Fig. 3b

< 0.01

0.625

 COPD

55.7 (37.4,74.1)

< 0.01

1.9 (1.2,2.5)

< 0.01

0.916

 Skin Cancer

48.1 (36.6132.9)

0.24

9.4 (−10.2,28.9)

0.31

0.296

  1. Model 1: adjusted for mean age, % male, % non-Hispanic White, prevalence of each chronic health condition
  2. Model 2: adjusted for mean age, % male, % non-Hispanic White, hospitalization rate of each chronic health condition
  3. Model 3: adjusted for mean age, % male, % non-Hispanic White, prevalence of each chronic health condition and hospitalization rate of each chronic health condition
  4. Abbreviations: ASHD Arteriosclerotic heart disease, CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease