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Table 3 Characteristic of hypercatabolic and less catabolic patients with severe NS

From: Protein energy-wasting associated with nephrotic syndrome – the comparison of metabolic pattern in severe nephrosis to different stages of chronic kidney disease

Variable Hypercatabolic NS
n = 9
Less catabolic NS
n = 11
p-value
History of NS
 short (< 1 month) n (%) 7 (77.8%) 3 (27.3%) 0.035
 long (1–3 months) n (%) 2 (22.2%) 8 (72.7%)  
Age [years] mean ± SD 37 ± 15 53 ± 16 0.043
Height [cm] mean ± SD 176 ± 16 172 ± 13 0.380
Weight [kg] mean ± SD 83 ± 16 83 ± 13 0.910
BMI [kg/m2] mean ± SD 27.9 ± 3.3 26.6 ± 3.7 0.423
eGFR [mL/min/1.73m2] mean ± SD 85 ± 28 81 ± 31 0.763
Serum creatinine [mg/dL] mean ± SD 1.13 ± 0.3 1.14 ± 0.3 0.982
Blood urea [mg/dL] mean ± SD 70 ± 41 38 ± 13 0.027
Serum albumin [g/dL] mean ± SD 1.8 ± 0.4 1.9 ± 0.3 0.538
Serum total protein [g/dL] mean ± SD 4.3 ± 0.4 4.3 ± 0.7 0.703
Proteinuria [g/day] mean ± SD 11.0 ± 6.2 11.9 ± 2.6 0.688
Prealbumin [mg/dL] median (IQR) 18 ± 6 26 ± 8 0.018
OH [L] mean ± SD 8.2 ± 5.8 3.8 ± 1.8 0.030
LTM [kg] adjusted for age mean ± SD 40.6 ± 2.4 45.8 ± 2.1 0.006*
B ± SE (95% CI) −5.6 ± 1.8 (−9.4; −1.9) ref
BCM [kg] adjusted for age mean ± SD 22.3 ± 1.6 25.6 ± 1.4 0.007*
B ± SE (95% CI) −3.7 ± 1.22 (−6.2; − 1.2) ref
  1. The average values of continuous variables were presented as mean ± SD or median (OQR). Laboratory parameters were compared between groups using independent samples t-test, and BIS parameters (*) using analysis of covariance (ANCOVA) – after an adjustment for age with less catabolic nephrotic patients as a reference group (ref), and described as coefficient (B) with standard error (SE), 95% confidence interval (95% CI). Statistically significant differences between groups (p-values < 0.05) were bolded