Fig. 4

Renal Function Safety Laboratory Tests. a Creatinine; b estimated glomerular filtration rate (eGFR); and c blood urea nitrogen (BUN) in patients treated with all doses of NRPT combined (all Steps) or placebo. Bl, baseline, prior to AKI; −24 h, at the time of enrollment; 0 h, immediately prior to first dose of NRPT or placebo; 24 h, at 24 h of treatment; 48 h, at 48 h of treatment