Table 1 Main characteristics of the included studies
From: Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis
Study | Country | Sample size | Mean age | Follow-up (year) | Percentage male(%) | survival | Risk factors | Definition of aging | NOS score |
|---|---|---|---|---|---|---|---|---|---|
Kutner 1994 [9] | USA | 287 | 69 | 3 | 51 | 24% of men,49% of women | Age,Sex, race, DM, CVD, Functional status | ≥60ys | 8 |
Jassal 1996 [10] | Ireland | 53 | 72.6 | 1 | 66 | 46.3% | Age, Alb, P | ≥65ys | 8 |
Kutner 2001 [11] | USA | 349 | 68.8 ± 6 | 11 | 49.5 | – | Age,BMI, CVD | ≥60ys | 8 |
Kurella 2006 [12] | USA | 16,694 | 60 ± 15 | – | 57 | – | dementia | – | 7 |
O’Hare2007 [12] | USA | 1949 | – | 3.2 | – | – | Age,eGFR | ≥65ys | 8 |
Li M 2008 [13] | Canada | 162 | 74.7 | 4 | 57 | 32.7 months | Falls | ≥65ys | 7 |
Canaud 2011 [14] | France | 8161 | – | 2 | 54.2 | 3.3 years | Age | ≥75ys | 9 |
Balogun 2011 [15] | USA | 77 | – | 5 | – | 3-year Survival38.5% | GDS-15 | ≥75ys | 7 |
Farrokhi 2013 [16] | Canada | 167 | 74.8 ± 5.9 | 5 | 57 | 54.4% | Functional impairment | ≥65ys | 7 |
Kim 2013 [17] | Korea | 290 | 79.1 ± 3.6 | 7.5 | 55.6 | 5-year Survival 53.1% | BP | ≥75ys | 8 |
Praga 2013 [18] | Germany | 1841 | 79.3 ± 3.4 | 5 | – | 15% | Vascular access, Gender, BMI, CHD, Stroke, HF, PVD, DM | ≥75ys | 9 |
Hatakeyam 2013 [19] | Japan | 141 | 84.2 ± 3.1 | 25 | 51.8 | – | Age, CVD, DM, BP, BMI, Hb, BUN, eGFR, Alb, P, K,Ca | ≥80ys | 7 |
Oliva 2013 [20] | Spain | 704 | 79.3 ± 3 | 3 | 55 | Mean survival 35 months | BMI, Vascular access, BP, CHF, CRP, Alb, Kt/V and time of dialysis session | ≥75ys | 8 |
Lin 2013 [21] | Taiwan | 10,759 | 79.9 ± 3.9 | 9 | 47 | – | age,sex, CCI | ≥75ys | 7 |
Glaudet 2013 [22] | France | 557 | – | 4 | 56.2 | 65.2% | dialysis initiation, DM, HF, impaired mobility,eGFR | ≥75ys | 7 |
Crews 2014 [23] | USA | 84,654 | 76.7 ± 6.3 | 2 | 58,.7 | 40.2% | dialysis initiation timing | ≥67ys | 8 |
Zingerman 2014 [24] | Israel | 29 | 88 ± 3 | 8 | 66 | 5-year Survival20% | Alb,Weekly HDx treatment time | >84ys | 6 |
Zhang 2014 [25] | Canada | 23,066 | – | 10 | – | 5-year Survival 48.6% | age, Vascular access, CCI, BMI, Hb, Alb, Egfr | ≥65ys | 7 |
Bowling 2015 [26] | USA | 27,913 | 81.7 | 6 | 44.7 | 12% | Frailty | ≥75ys | 8 |
Seckinger 2016 [27] | Germany | 796 | 80.2 ± 3.9 | 2 | – | – | age, BMI,CCI, Hb,FACT-An score,CVD | ≥65ys | 6 |
Park 2017 [28] | Korea | 665 | 71.7 ± 5.3 | 7 | 60.2 | 28.3% | Early dialysis initiation | ≥65ys | 8 |
Feng 2017 [29] | Singapore | 1372 | – | 3 | 67.9 | – | Early initiation of dialysis | ≥65ys | 7 |
Lee 2017 [30] | Korea | 46 | 71.5 | 1 | 63 | – | Frailty | ≥65ys | 7 |
Tuğcu 2018 [19] | Turkey | 99 | 75 ± 7 | 4 | 47.6 | 47.5% | Age, ECOGS | > 65 ys | 6 |
Hall 2018 [31] | USA | 3500 | 80.5 | 2 | 50.1 | 71.9% | KDQOL-36 | ≥75ys | 8 |
Naka 2018 [32] | Japan | 118 | 85.5 | 1 | 18 | 88% | traditional risk factors,comorbidity index,frailty | ≥70ys | 7 |
Bowling 2018 [33] | NC | 81,653 | 76.8 ± 6.5 | 1 | 52.8 | 73.9% | falls | ≥67ys | 7 |
van Loon 2019 [18] | Netherlands | 196 | 75 ± 7 | 1 | 67 | 85% | geriatric assessment | ≥65ys | 8 |