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Table 1 Main characteristics of the included studies

From: Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis

Study Country Sample size Mean age Follow-up (year) Percentage male(%) survival Risk factors Definition of aging NOS score
Kutner 1994 [9] USA 287 69 3 51 24% of men,49% of women Age,Sex, race, DM, CVD, Functional status ≥60ys 8
Jassal 1996 [10] Ireland 53 72.6 1 66 46.3% Age, Alb, P ≥65ys 8
Kutner 2001 [11] USA 349 68.8 ± 6 11 49.5 Age,BMI, CVD ≥60ys 8
Kurella 2006 [12] USA 16,694 60 ± 15 57 dementia 7
O’Hare2007 [12] USA 1949 3.2 Age,eGFR ≥65ys 8
Li M 2008 [13] Canada 162 74.7 4 57 32.7 months Falls ≥65ys 7
Canaud 2011 [14] France 8161 2 54.2 3.3 years Age ≥75ys 9
Balogun 2011 [15] USA 77 5 3-year Survival38.5% GDS-15 ≥75ys 7
Farrokhi 2013 [16] Canada 167 74.8 ± 5.9 5 57 54.4% Functional impairment ≥65ys 7
Kim 2013 [17] Korea 290 79.1 ± 3.6 7.5 55.6 5-year Survival 53.1% BP ≥75ys 8
Praga 2013 [18] Germany 1841 79.3 ± 3.4 5 15% Vascular access, Gender, BMI, CHD, Stroke, HF, PVD, DM ≥75ys 9
Hatakeyam 2013 [19] Japan 141 84.2 ± 3.1 25 51.8 Age, CVD, DM, BP, BMI, Hb, BUN, eGFR, Alb, P, K,Ca ≥80ys 7
Oliva 2013 [20] Spain 704 79.3 ± 3 3 55 Mean survival 35 months BMI, Vascular access, BP, CHF, CRP, Alb, Kt/V and time of dialysis session ≥75ys 8
Lin 2013 [21] Taiwan 10,759 79.9 ± 3.9 9 47 age,sex, CCI ≥75ys 7
Glaudet 2013 [22] France 557 4 56.2 65.2% dialysis initiation, DM, HF, impaired mobility,eGFR ≥75ys 7
Crews 2014 [23] USA 84,654 76.7 ± 6.3 2 58,.7 40.2% dialysis initiation timing ≥67ys 8
Zingerman 2014 [24] Israel 29 88 ± 3 8 66 5-year Survival20% Alb,Weekly HDx treatment time >84ys 6
Zhang 2014 [25] Canada 23,066 10 5-year Survival 48.6% age, Vascular access, CCI, BMI, Hb, Alb, Egfr ≥65ys 7
Bowling 2015 [26] USA 27,913 81.7 6 44.7 12% Frailty ≥75ys 8
Seckinger 2016 [27] Germany 796 80.2 ± 3.9 2 age, BMI,CCI, Hb,FACT-An score,CVD ≥65ys 6
Park 2017 [28] Korea 665 71.7 ± 5.3 7 60.2 28.3% Early dialysis initiation ≥65ys 8
Feng 2017 [29] Singapore 1372 3 67.9 Early initiation of dialysis ≥65ys 7
Lee 2017 [30] Korea 46 71.5 1 63 Frailty ≥65ys 7
Tuğcu 2018 [19] Turkey 99 75 ± 7 4 47.6 47.5% Age, ECOGS > 65 ys 6
Hall 2018 [31] USA 3500 80.5 2 50.1 71.9% KDQOL-36 ≥75ys 8
Naka 2018 [32] Japan 118 85.5 1 18 88% traditional risk factors,comorbidity index,frailty ≥70ys 7
Bowling 2018 [33] NC 81,653 76.8 ± 6.5 1 52.8 73.9% falls ≥67ys 7
van Loon 2019 [18] Netherlands 196 75 ± 7 1 67 85% geriatric assessment ≥65ys 8