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Fig. 1 | BMC Nephrology

Fig. 1

From: Complete remission of nephrotic syndrome in a young woman with anti-LRP2 nephropathy after immunosuppressive therapy

Fig. 1

Characteristic morphology of kidney biopsy in this case. a-b Glomeruli were without morphologic abnormalities and no obvious tubular injury. (a: Periodic acid Schiff PAS, original magnification × 400; b: Periodic acid Schiff PAS, original magnification× 100). c IgG staining along the brush border of proximal tubular cells, some TBMs, Bowman’s capsule and small segmental granular deposits along GBM (direct immunofluorescence, original magnification × 400). d C3 staining along TBMs, Bowman’s capsule and small segmental granular deposits along GBM (original magnification × 400). e IgG1 was present in the brush border of proximal tubular cells, TBM and GBM (original magnification × 400). f-g Immunohistochemistry for C4d revealed segmentally sparse deposits along GBM (f) and TBM (g) (original magnification × 600). h-i Electron microscopy (h) of glomeruli presented foot process effacement without electron-dense deposits (original magnification × 6000). i Small granular electron-dense deposits within the proximal TBMs (original magnification × 15,000)

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